Mostrando 6 resultados de: 6
Filtros aplicados
Subtipo de publicación
Article(6)
Publisher
ACS Infectious Diseases(1)
Amino Acids(1)
Bioorganic and Medicinal Chemistry Letters(1)
ChemBioChem(1)
Journal of Medicinal Chemistry(1)
Área temáticas
Farmacología y terapéutica(4)
Microorganismos, hongos y algas(4)
Bioquímica(3)
Fisiología y materias afines(1)
Química orgánica(1)
Origen
scopus(6)
A BODIPY-embedding miltefosine analog linked to cell-penetrating Tat(48-60) peptide favors intracellular delivery and visualization of the antiparasitic drug
ArticleAbstract: Therapeutic application of many drugs is often hampered by poor or denied access to intracellular taPalabras claves:BODIPY, cell-penetrating peptide, Dual fluorescent labeling, Miltefosine, Monitoring of intracellular drug delivery, Reversion of resistanceAutores:Abengózar M.Á., Amat-Guerri F., Andreu D., B. G. De la Torre, Hornillos V., Luque-Ortega J.R., Rivas L., Ulises Acuña A.Fuentes:scopusEssential Role of Enzymatic Activity in the Leishmanicidal Mechanism of the Eosinophil Cationic Protein (RNase 3)
ArticleAbstract: The recruitment of eosinophils into Leishmania lesions is frequently associated with a favorable evoPalabras claves:Antimicrobial peptide, cell-penetrating enzyme, membrane disruption, protozoa, RNaseAutores:Abengózar M.Á., Andreu D., B. G. De la Torre, Boix E., Fernández-Reyes M., Rivas L., Salazar V.A., Torrent M.Fuentes:scopusInfluence of lysine N<sup>ε</sup>-trimethylation and lipid composition on the membrane activity of the cecropin A-melittin hybrid peptide CA(1-7)M(2-9)
ArticleAbstract: Although many studies have pointed out the promising role of antimicrobial peptides (AMPs) as therapPalabras claves:Autores:Andreu D., B. G. De la Torre, Bastos M., Coutinho A., Feio M.J., Rivas L., Teixeira V.Fuentes:scopusLysine N <sup>ε</sup>-trimethylation, a tool for improving the selectivity of antimicrobial peptides
ArticleAbstract: The effects of lysine N?-trimethylation at selected positions of the antimicrobial cecropin A?melittPalabras claves:Autores:Andreu D., B. G. De la Torre, Cabrales-Rico A., Díaz D., Fernández-Reyes M., Jiménez-Barbero J., Rivas L., Vallès-Miret M.Fuentes:scopusStructural framework for the modulation of the activity of the hybrid antibiotic peptide cecropin A-melittin [CA(1-7)M(2-9)] by N <sup>ε</sup>-lysine trimethylation
ArticleAbstract: The 3D structures of six linear pentadecapeptides derived from the cecropin A-melittin antimicrobialPalabras claves:Antimicrobial peptides (AMPs), cecropin A, membranes, NMR spectroscopy, TrimethyllysineAutores:Andreu D., B. G. De la Torre, Díaz M.D., Fernández-Reyes M., Jiménez-Barbero J., Rivas L.Fuentes:scopusSynthesis of 16-mercaptohexadecylphosphocholine, a miltefosine analog with leishmanicidal activity
ArticleAbstract: The alkylphosphocholine miltefosine (n-hexadecylphosphocholine, MT) has been introduced recently asPalabras claves:Hexadecylphosphocholine, LEISHMANIA, Mercaptophosphocholine, Miltefosine, ParasiticideAutores:Acuña A.U., Amat-Guerri F., Andreu D., B. G. De la Torre, Hornillos V., Rivas L., Saugar J.M.Fuentes:scopus