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Biochimica et Biophysica Acta - Molecular Cell Research(1)
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Influence of lysine N<sup>ε</sup>-trimethylation and lipid composition on the membrane activity of the cecropin A-melittin hybrid peptide CA(1-7)M(2-9)
ArticleAbstract: Although many studies have pointed out the promising role of antimicrobial peptides (AMPs) as therapPalabras claves:Autores:Andreu D., B. G. De la Torre, Bastos M., Coutinho A., Feio M.J., Rivas L., Teixeira V.Fuentes:scopusLysine N <sup>ε</sup>-trimethylation, a tool for improving the selectivity of antimicrobial peptides
ArticleAbstract: The effects of lysine N?-trimethylation at selected positions of the antimicrobial cecropin A?melittPalabras claves:Autores:Andreu D., B. G. De la Torre, Cabrales-Rico A., Díaz D., Fernández-Reyes M., Jiménez-Barbero J., Rivas L., Vallès-Miret M.Fuentes:scopusStructural framework for the modulation of the activity of the hybrid antibiotic peptide cecropin A-melittin [CA(1-7)M(2-9)] by N <sup>ε</sup>-lysine trimethylation
ArticleAbstract: The 3D structures of six linear pentadecapeptides derived from the cecropin A-melittin antimicrobialPalabras claves:Antimicrobial peptides (AMPs), cecropin A, membranes, NMR spectroscopy, TrimethyllysineAutores:Andreu D., B. G. De la Torre, Díaz M.D., Fernández-Reyes M., Jiménez-Barbero J., Rivas L.Fuentes:scopusThe induction of NOS2 expression by the hybrid cecropin A-melittin antibiotic peptide CA(1-8)M(1-18) in the monocytic line RAW 264.7 is triggered by a temporary and reversible plasma membrane permeation
ArticleAbstract: There is an increasing awareness of immune cell modulation by antimicrobial peptides. While this proPalabras claves:Antimicrobial peptide, Cecropin A-melittin, electrophysiology, macrophageAutores:Andreu D., Arias C., B. G. De la Torre, Guerrero E., Guizy M., Luque-Ortega J.R., Rivas L., Valenzuela C.Fuentes:scopus