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Molecules(5)
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Antifungal activity of n-(4-halobenzyl)amides against candida spp. and molecular modeling studies
ArticleAbstract: Fungal infections remain a high-incidence worldwide health problem that is aggravated by limited thePalabras claves:Anticandidal drugs, antimicrobial activity, Benzoic acid, Candida auris, Candidiasis, cinnamic acid, fungi, Molecular docking, Natural products, plantsAutores:da Silva C.R., Dias C.d.S., Duarte A.B.S., Júnior H.V.N., Montes R.C., Neto J.B.d.A., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusAntileishmanial Activity of Cinnamic Acid Derivatives against Leishmania infantum
ArticleAbstract: Leishmania infantum is the etiological agent of visceral leishmaniasis (VL) in South America, the MePalabras claves:antiparasitic activity, cinnamamide, cinnamate, Medicinal Plant, Natural productAutores:Almeida F.S., de Morais M.C., Keesen T.d.S.L., Medeiros G.A., Rocha J.d.C., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopus3,5-Dinitrobenzoate and 3,5-Dinitrobenzamide Derivatives: Mechanistic, Antifungal, and in Silico Studies
ArticleAbstract: Fungal infections, including those caused by Candida spp., are recognized in immunocompromised indivPalabras claves:Autores:Andrade P.N., De Castro R.D., Duarte A.B.S., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusCytotoxic and antifungal amides derived from ferulic acid: Molecular docking and mechanism of action
ArticleAbstract: Amides derived from ferulic acid have a wide spectrum of pharmacological activities, including antitPalabras claves:Autores:Bezerra D.P., De Castro R.D., de Morais M.C., de Souza Santos L., Silva V.R., Soares M.B.P., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusArticle bioactive terpenes and their derivatives as potential SARS-CoV-2 proteases inhibitors from molecular modeling studies
ArticleAbstract: The coronavirus disease 2019 (COVID-19) pandemic is caused by a novel coronavirus; the Severe AcutePalabras claves:covid-19, MERS-CoV, Middle East Respiratory Syndrome Virus, Natural products, plants, saponins, SARS-CoV, SARS-COV-2, Terpenoid, virusesAutores:Bezerra Filho C.d.S.M., Diniz L.R.L., Elshabrawy H.A., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusAlkyl and aryl derivatives based on p-coumaric acid modification and inhibitory action against leishmania braziliensis and plasmodium falciparum
ArticleAbstract: In low-income populations, neglected diseases are the principal cause of mortality. Of these, leishmPalabras claves:Antiplasmodial activity, Cytotoxicity, Hydroxycinnamic acids, Leishmanicidal activity, Natural products, Neglected diseasesAutores:Lopes S.P., Robledo S.M., Sousa D.P.D., Yepe L.M., Yunierkis Perez-CastilloFuentes:googlescopusDesign, Antileishmanial Activity, and QSAR Studies of a Series of Piplartine Analogues
ArticleAbstract: Piplartine is an alkamide found in different Piper species and possesses several biological activitiPalabras claves:Autores:Bezerra D.P., Bezerra Filho C.d.S.M., Lima T.C., Lima T.K.S., Nóbrega F.R., Silva L.V., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopusGallic Acid Alkyl Esters: Trypanocidal and Leishmanicidal Activity, and Target Identification via Modeling Studies
ArticleAbstract: Eight gallic acid alkyl esters (1–8) were synthesized via Fischer esterification and evaluated for tPalabras claves:gallic acid alkyl ester, Leishmania major, Leishmanicidal activity, Molecular docking, molecular dynamics simulations, Natural products, trypanocidal activity, Trypanosoma bruceiAutores:do Nascimento L.G., Sousa D.P.D., Steverding D., Yunierkis Perez-CastilloFuentes:googlescopusNFBTA: A potent cytotoxic agent against glioblastoma
ArticleAbstract: Piplartine (PPL), also known as piperlongumine, is a biologically active alkaloid extracted from thePalabras claves:Analogue, ANTICANCER, Antiglioblastoma therapy, Piper, PiplartineAutores:De Almeida R.N., Eduardo Tejera, Filho C.D.S.M.B., Nóbrega F.R., Ozdemir O., Sousa D.P.D., Turkez H., Yunierkis Perez-CastilloFuentes:googlescopusTrypanocidal mechanism of action and in silico studies of p-coumaric acid derivatives
ArticleAbstract: Trypanosoma species are responsible for chronic and systemic infections in millions of people aroundPalabras claves:antiparasitic activity, cinnamic acid, esters, Natural products, Neglected diseases, Phenylpropanoid, TrypanosomaAutores:De Almeida R.N., de Menezes R.R.P.P.B., Lopes S.P., Martins A.M.C., Monteiro M.L., Sousa D.P.D., Yunierkis Perez-CastilloFuentes:googlescopus