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Bacteria Hunt Bacteria through an Intriguing Cyclic Peptide
ReviewAbstract: In the last few decades, peptides have been victorious over small molecules as therapeutics due to tPalabras claves:Antibiotics, biological activity, cyclic antimicrobial peptides, Drug Discovery, PeptidesAutores:Alberício F., B. G. De la Torre, El-Faham A., Monaim S.A.H.A., Somboro A.M.Fuentes:scopus1,3,5-Triazino Peptide Derivatives: Synthesis, Characterization, and Preliminary Antileishmanial Activity
ArticleAbstract: A library of short di-, tri-, and tetra-peptides with an s-triazine moiety at the N terminus and eitPalabras claves:1,3,5-triazine derivatives, antileishmanial compounds, morpholines, Peptides, piperidinesAutores:Abd El-Rahman M.M., Alberício F., B. G. De la Torre, Bekhit A.A., El-Faham A., Khalil H.H., Khattab S.N.Fuentes:scopusConverting Teixobactin into a Cationic Antimicrobial Peptide (AMP)
ArticleAbstract: Teixobactin is a head to side chain cyclodepsipeptide that contains two positive charges. One is fouPalabras claves:Autores:Alberício F., B. G. De la Torre, El-Faham A., Monaim S.A.H.A., Ramchuran E.J.Fuentes:scopusGreen Solid-Phase Peptide Synthesis (GSPPS) 3. Green Solvents for Fmoc Removal in Peptide Chemistry
ArticleAbstract: DMF (N,N-dimethylformamide) is the most widely used solvent for Fmoc-SPPS, which is the conventionalPalabras claves:Fmoc, Green solvents, Peptide aggregation, Protecting groups, Solid-phase peptide synthesis, valerolactoneAutores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Kruger H.G.Fuentes:scopusGreen Solid-Phase Peptide Synthesis 2. 2-Methyltetrahydrofuran and Ethyl Acetate for Solid-Phase Peptide Synthesis under Green Conditions
ArticleAbstract: N,N-Dimethylformamide (DMF), N-methyl-2-pyrrolidone, and dichloromethane (DCM) are the most widely uPalabras claves:2-MeTHF, Green Chemistry, Peptide aggregation, Polyethylene glycol resins, Solid-phase peptide synthesis, solid-phase synthesisAutores:Acosta G.A., Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Kruger H.G.Fuentes:scopusGreen Transformation of Solid-Phase Peptide Synthesis
ReviewAbstract: Peptides play key roles in medicinal chemistry, being found in therapeutics and diagnostic agents, aPalabras claves:Green Chemistry, Green solvents, Parallel synthesis, Peptide synthesis, solid-phase synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusGreening the Solid-Phase Peptide Synthesis Process. 2-MeTHF for the Incorporation of the First Amino Acid and Precipitation of Peptides after Global Deprotection
ArticleAbstract: In solid-phase peptide synthesis, dichloromethane is the predominant solvent used to incorporate thePalabras claves:2-MeTHF, Dipeptide formation, incorporation, precipitation, Racemization, Solid-phase peptide synthesisAutores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A., Collins J.M., El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusExploiting azido-dichloro-triazine as a linker for regioselective incorporation of peptides through their N, O, S functional groups
ArticleAbstract: In the field of bioconjugation, linker development has witnessed massive growth in recent years. 2,4Palabras claves:Bioconjuation, Linker, Orthogonal chemoselectivity, Orthogonality, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Kumar A., Sharma A.Fuentes:scopusEDC·HCl and Potassium Salts of Oxyma and Oxyma-B as Superior Coupling Cocktails for Peptide Synthesis
ArticleAbstract: Nowadays, DIC is the most widely used carbodiimide for solid-phase peptide synthesis, while EDC·HClPalabras claves:peptide coupling, Peptides, solid-phase synthesis, Steric hindrance, synthetic methodsAutores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Khattab S.N., Kruger H.G.Fuentes:scopusN-methylation in amino acids and peptides: Scope and limitations
ReviewAbstract: Active pharmaceutical ingbkp_redients (APIs) can be divided into two types, namely chemical and biolPalabras claves:cyclic peptides, NMAA, side-reactions, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A., Monaim S.A.H.A., Sharma A.Fuentes:scopus