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Bypassing osmotic shock dilemma in a polystyrene resin using the green solvent cyclopentyl methyl ether (CPME): A morphological perspective
ArticleAbstract: The "osmotic shock" phenomenon is the main thing that is responsible for morphological structure altPalabras claves:Green solvent, Osmotic shock, Solid-phase peptide synthesisAutores:Al Musaimi O., Alberício F., Almarhoon Z.M., B. G. De la Torre, Basso A., El-Faham A.Fuentes:scopusCorrigendum: Pyrazolyl-s-triazine with indole motif as a novel of epidermal growth factor receptor/cyclin-dependent kinase 2 dual inhibitors(Front. Chem., (2022), 10, (1078163), 10.3389/fchem.2022.1078163)
OtherAbstract: In the original article, there was an error in the Affiliation for Samha Al Ayoubi2. Instead of “SamPalabras claves:anticancer profile, apoptosis, EGFR/CDK-2, ÍNDOLE, pyrazolyl-s-triazineAutores:Al Ayoubi S., Al Zoubi M., Al-Rasheed H.H., Alberício F., Aldalbahi A., Ali M., Alshaer W., B. G. De la Torre, Barakat A., El-Faham A., Nafie M.S., Shawish I.Fuentes:scopusCrystal structure and theoretical investigation of thiobarbituric acid derivatives as nonlinear optical (NLO) materials
ArticleAbstract: Here we report on the crystal structure of three enamine/imine TBA derivatives (1−3). Since the deriPalabras claves:Crystals, DFT, Enamine/imine tautomer, Hyperpolarizability, NLOAutores:Al-Majid A.M., Al-Rasheed H.H., Alberício F., B. G. De la Torre, Barakat A., Choudhary M.I., El-Faham A., Sharma A., Yousuf S.Fuentes:scopusAcetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) via EGFR/PI3K/AKT/mTOR Signaling Cascades
ArticleAbstract: Here, we described the synthesis of novel pyrazole-s-triazine derivatives via an easy one-pot procedPalabras claves:anticancer profile, apoptosis, DMF-DMA, EGFR/PI3K/AKT/mTOR, One-pot synthesis, pyrazolyl-s-triazineAutores:Al Zoubi M., Alberício F., Aldalbahi A., Alqudah D.A., Alshaer W., B. G. De la Torre, Barakat A., Daoud F., El-Faham A., Hatmal M.M., Haukka M., Nafie M.S., Sharma A., Shawish I.Fuentes:scopusGreen Transformation of Solid-Phase Peptide Synthesis
ReviewAbstract: Peptides play key roles in medicinal chemistry, being found in therapeutics and diagnostic agents, aPalabras claves:Green Chemistry, Green solvents, Parallel synthesis, Peptide synthesis, solid-phase synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusExploiting azido-dichloro-triazine as a linker for regioselective incorporation of peptides through their N, O, S functional groups
ArticleAbstract: In the field of bioconjugation, linker development has witnessed massive growth in recent years. 2,4Palabras claves:Bioconjuation, Linker, Orthogonal chemoselectivity, Orthogonality, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Kumar A., Sharma A.Fuentes:scopusPhenol as a modulator in the chemical reactivity of 2,4,6-Trichloro-1,3,5-triazine: Rules of the Game II
ArticleAbstract: 2,4,6-Trichloro-1,3,5-triazine (TCT) is a privileged core that has the capacity to undergo sequentiaPalabras claves:Autores:Alberício F., B. G. De la Torre, El-Faham A., Sharma A., Sheyi R.Fuentes:scopusInvestigation of the N-terminus amino function of Arg<inf>10</inf>-Teixobactin
ArticleAbstract: Teixobactin is a recently described antimicrobial peptide that shows high activity against gram-posiPalabras claves:Antimicrobial peptides, Cyclic depsipeptides, Lipophilicity, Solid-phase peptide synthesis, TeixobactinAutores:Alberício F., B. G. De la Torre, El-Faham A., Monaim S.A.H.A., Noki S., Ramchuran E.J.Fuentes:scopusProtocol for synthesis of di- and tri-substituted s-triazine derivatives
ArticleAbstract: The present protocol describes the synthesis of di and tri-substituted s-triazine derivatives • s-TrPalabras claves:ALCOHOL, amines, Cyanuric chloride, Nucleophilic substitution, Orthogonal chemoselectivity, Sequential nucleophilic substitutionAutores:Alberício F., Alhameed R.A., Almarhoon Z.M., B. G. De la Torre, El-Faham A., Farooq M., Sharma A., Wadaan M.A.M.Fuentes:scopusγ-Valerolactone (GVL): An eco-friendly anchoring solvent for solid-phase peptide synthesis
ArticleAbstract: Due to the hazardous nature of CH2Cl2, regulatory authorities have imposed restrictions to minimizePalabras claves:Dipeptide formation, Green Chemistry, Racemization, Wang resinAutores:Al Musaimi O., Alberício F., B. G. De la Torre, Basso A., El-Faham A.Fuentes:scopus