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1,3,5-Triazine as core for the preparation of dendrons
ArticleAbstract: A unique property of 2,4,6-trichloro-1,3,5-triazine (TCT) is its ability to undergoes a nucleophilicPalabras claves:1+2 mode, Dendron, HPLC, Nucleophiles, S-triazineAutores:Alberício F., B. G. De la Torre, El-Faham A., Kumar A., Sharma A., Sheyi R.Fuentes:scopusDesign and synthesis of mono-and di-pyrazolyl-s-triazine derivatives, their anticancer profile in human cancer cell lines, and in vivo toxicity in zebrafish embryos
ArticleAbstract: s-Triazine is considered a privileged structure, as it is found in several FDA-approved drugs. In thPalabras claves:anticancer activity, Pyrazole, S-triazine, Zebrafish embryosAutores:Al-Dhfyan A., Alberício F., Almarhoon Z.M., B. G. De la Torre, El-Faham A., Farooq M., Sharma A., Taha N.A., Wadaan M.A.M.Fuentes:scopusExploring the orthogonal chemoselectivity of 2,4,6-trichloro-1,3,5-triazine (TCT) as a trifunctional linker with different nucleophiles: Rules of the game
ArticleAbstract: The study involves exploring the three orthogonal sites for aromatic nucleophilic substitution in cyPalabras claves:density functional theory, Electrostatic potential maps, NBO calculations, S-triazine, Triorthogonal linkerAutores:Alberício F., B. G. De la Torre, El-Faham A., Sharma A.Fuentes:scopusS-triazine: A privileged structure for drug discovery and bioconjugation
ArticleAbstract: This review provides an overview of the broad applicability of s-triazine. Our many years working wiPalabras claves:azide, Nucleophiles, Orthogonal chemoselectivity, S-triazineAutores:Alberício F., B. G. De la Torre, El-Faham A., Sharma A., Sheyi R.Fuentes:scopusThe antiproliferative and apoptotic effect of a novel synthesized s-triazine dipeptide series, and toxicity screening in zebrafish embryos
ArticleAbstract: Several derivatives containing morpholine/piperidine, anilines, and dipeptides as pending moieties wPalabras claves:Anti-proliferative activity, apoptosis, Dipeptides, S-triazine, zebrafishAutores:Alberício F., Alhameed R.A., Almarhoon Z.M., B. G. De la Torre, El-Faham A., Farooq M., Malebari A.M., Sharma A., Wadaan M.A.M.Fuentes:scopus