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Converting Teixobactin into a Cationic Antimicrobial Peptide (AMP)
ArticleAbstract: Teixobactin is a head to side chain cyclodepsipeptide that contains two positive charges. One is fouPalabras claves:Autores:Alberício F., B. G. De la Torre, El-Faham A., Monaim S.A.H.A., Ramchuran E.J.Fuentes:scopusGreen Solid-Phase Peptide Synthesis (GSPPS) 3. Green Solvents for Fmoc Removal in Peptide Chemistry
ArticleAbstract: DMF (N,N-dimethylformamide) is the most widely used solvent for Fmoc-SPPS, which is the conventionalPalabras claves:Fmoc, Green solvents, Peptide aggregation, Protecting groups, Solid-phase peptide synthesis, valerolactoneAutores:Alberício F., B. G. De la Torre, El-Faham A., Govender T., Jad Y.E., Kruger H.G.Fuentes:scopusGreen solid-phase peptide synthesis 4. γ-Valerolactone and N-formylmorpholine as green solvents for solid phase peptide synthesis
ArticleAbstract: Herein, we report the use of γ-valerolactone (GVL) and N-formylmorpholine (NFM) as DMF substitutes iPalabras claves:Green solvents, GVL, NFM, polystyrene resin, Solid-phase peptide synthesisAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusFmoc-Amox, A Suitable Reagent for the Introduction of Fmoc
ArticleAbstract: Synthesis of most peptides is achieved using solid-phase peptide synthesis employing the Fmoc/tert-bPalabras claves:Autores:Alberício F., B. G. De la Torre, El-Faham A., Haimov E., Kumar A., Sharma A.Fuentes:scopusNovel pyrazolyl-s-triazine derivatives, molecular structure and antimicrobial activity
ArticleAbstract: A new series of pyrazole-containing s-triazine derivatives were synthesized by reaction of the correPalabras claves:Antibacterial activities, Cyanuric chloride, DFT/B3LYP, Hydrazino-s-triazine, Pyrazole, X-ray crystallographyAutores:Alberício F., B. G. De la Torre, El-Faham A., Ghabbour H.A., Khan S.T., Sharma A.Fuentes:scopusInvestigation of the N-terminus amino function of Arg<inf>10</inf>-Teixobactin
ArticleAbstract: Teixobactin is a recently described antimicrobial peptide that shows high activity against gram-posiPalabras claves:Antimicrobial peptides, Cyclic depsipeptides, Lipophilicity, Solid-phase peptide synthesis, TeixobactinAutores:Alberício F., B. G. De la Torre, El-Faham A., Monaim S.A.H.A., Noki S., Ramchuran E.J.Fuentes:scopusUnderstanding Tetrahydropyranyl as a Protecting Group in Peptide Chemistry
ReviewAbstract: Tetrahydropyranyl (Thp) is recognized as a useful protecting group for alcohols in organic synthesisPalabras claves:3,4-dihydro-2H-pyran, hydroxyl groups, Protecting groups, tetrahydropyranyl group, ThiolsAutores:Alberício F., B. G. De la Torre, El-Faham A., Hortensia Rodriguez Cabrera, Nicolas E., Ramos-Tomillero I., Sharma A.Fuentes:googlescopusRe-evaluating the stability of COMU in different solvents
ArticleAbstract: COMU is uronium-type coupling reagent based on OxymaPure. It showed several advantages over classicaPalabras claves:COMU, Green solvent, peptide-coupling reagent, Solid-phase peptide synthesis, γ-valerolactoneAutores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Kumar A.Fuentes:scopusSynthesis, Characterization, and Tautomerism of 1,3-Dimethyl Pyrimidine-2,4,6-Trione s-Triazinyl Hydrazine/Hydrazone Derivatives
ArticleAbstract: 1,3,5-Triazines and pyrimidine-2,4,6-triones belong to that class of compounds which are well knownPalabras claves:Autores:Alberício F., B. G. De la Torre, El-Faham A., Jad Y.E., Sharma A., Siddiqui M.R.H.Fuentes:scopusSynthesis, crystal structure and DFT studies of 1,3-dimethyl-5-propionylpyrimidine-2,4,6(1H,3H,5H)-trione
ArticleAbstract: Novel 1,3-Dimethyl-5-propionylpyrimidine-2,4,6(1H,3H,5H)-trione was synthesized and recrystallized fPalabras claves:1,3-dimethylpyrimidine-2,4,6-trione, DFT molecular orbital calculations, HOMO, LUMO, X-rayAutores:Alberício F., B. G. De la Torre, El-Faham A., Ghabbour H.A., Jad Y.E., Kruger H.G., Sharma A.Fuentes:scopus