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CYP2D6-1584C>G promoter polymorphism and debrisoquine ultrarapid hydroxylation in healthy volunteers
ArticleAbstract: Background & aim: The CYP2D6-1584C>G polymorphism (rs1080985) has been identified as a major factorPalabras claves:1584C>G, CYP2D6, debrisoquine, Healthy volunteers, ultrarapid metabolismAutores:Adrián LLerena, Alvárez M., Calzadilla L.R., Dorado P., González I., Naranjo M.E.G., Penãs-Lledó E.M., Pérez B., Ramirez R.Fuentes:scopusRelation between CYP2D6 genotype, personality, neurocognition and overall psychopathology in healthy volunteers
Conference ObjectAbstract: Aims: A lower serotonin/higher dopamine tone in CYP2D6 poor metabolizers (PMs) versus extensive metaPalabras claves:CANTAB®, CYP2D6, Impulsivity, KSP, personality, pharmacogenetics, Pharmacogenomics, SCL-90-R, TCI-RAutores:Adrián LLerena, Dorado P., González I., Pacheco R., Penãs-Lledó E.M.Fuentes:scopusRelation between CYP2D6 phenotype and genotype and personality in healthy volunteers
ArticleAbstract: Objectives: Our group has previously show that interindividual variability in CYP2D6 hydroxylation cPalabras claves:anxiety, CYP2D6, debrisoquine, KSP, personality, pharmacogenetics, PharmacogenomicsAutores:Adrián LLerena, Alvárez M., Dorado P., González I., Penãs-Lledó E.M., Pérez B.Fuentes:scopus