Mostrando 2 resultados de: 2
Subtipo de publicación
Article(2)
Origen
scopus(2)
Conservative mutations of glutamine-125 in herpes simplex virus type 1 thymidine kinase result in a ganciclovir kinase with minimal deoxypyrimidine kinase activities
ArticleAbstract: The herpes simplex virus type 1 thymidine kinase (HSV-1 TK) is the major anti-herpes virus pharmacolPalabras claves:Autores:Cesar M. Compadre, Drake R.R., Hinds T., Hurlburt B.Fuentes:scopusMutation of herpesvirus thymidine kinase to generate ganciclovir-specific kinases for use in cancer gene therapies
ArticleAbstract: Understanding the functional and mechanistic properties of the multi-substrate herpes simplex virusPalabras claves:Ganciclovir, Gene therapy, Thymidine, Thymidine kinase, Thymidylate kinaseAutores:Ahn C.E., Cesar M. Compadre, Coke A., Drake R.R., Mercer K.E.Fuentes:scopus