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Bioorganic and Medicinal Chemistry(1)
European Journal of Medicinal Chemistry(1)
Journal of Industrial Microbiology and Biotechnology(1)
Life Sciences(1)
Medicinal Chemistry(1)
Antifungal activity of a novel chromene dimer
ArticleAbstract: The activity on Aspergillus spp. growth and on ochratoxin A production of two novel chromene dimersPalabras claves:Antifungal compounds, Aspergillus spp., Chromenes, Ochratoxin AAutores:Abrunhosa L., Costa M., Filipe Miguel Areias, Proença M.F., Venâncio A.Fuentes:googlescopus2-Aryladenine derivatives as a potent scaffold for A<inf>1</inf>, A<inf>3</inf> and dual A<inf>1</inf>/A<inf>3</inf> adenosine receptor antagonists: Synthesis and structure-activity relationships
ArticleAbstract: From a collection containing more than 1500 academic compounds, in silico screening identified a hitPalabras claves:2-Arylpurine derivatives, Adenine derivatives, Adenosine receptor antagonistsAutores:Brea J., Carvalho M.A., Castro M., Correia C., Filipe Miguel Areias, Loza M.I., Proença M.F., Rocha A.Fuentes:googlescopusNew chromene scaffolds for adenosine A<inf>2A</inf> receptors: Synthesis, pharmacology and structure-activity relationships
ArticleAbstract: In silico screening of a collection of 1584 academic compounds identified a small molecule hit for tPalabras claves:Adenosine receptors, Chromene scaffolds, G protein-coupled receptors, Knoevenagel condensation, Structure-activity relationshipAutores:Brea J., Castro M., Costa M., Filipe Miguel Areias, Gregori-Puigjané E., Loza M.I., Mestres J., Proença M.F.Fuentes:googlescopusOxidative stress protection by newly synthesized nitrogen compounds with pharmacological potential
ArticleAbstract: In this study we used new nitrogen compounds obtained by organic synthesis whose structure pbkp_rediPalabras claves:Antioxidants, Cell apoptosis, Lipid peroxidation, Nitrogen compounds, Oxidative StressAutores:Coutinho O.P., Filipe Miguel Areias, Proença M.F., Silva J.P.Fuentes:googlescopusPhenolic imidazole derivatives with dual antioxidant/antifungal activity: Synthesis and structure-activity relationship
ArticleAbstract: Background: Previous publications show that the addition of a phenolic antioxidant to an antifungalPalabras claves:Antifungal activity, Antioxidant activity, Cáncer, Phenolic imidazoles, Phenolic purines, Structure-activity relationshipAutores:Bettencourt A.P., Castro M., Coutinho O.P., Fernandes F., Filipe Miguel Areias, Proença M.F., Silva J.P., Sousa M.J.Fuentes:googlescopusSynthesis of novel chromene scaffolds for adenosine receptors
ArticleAbstract: A one-pot procedure was developed for the synthesis of novel 3-[amino(methoxy)methylene]-2-oxo-3,4-dPalabras claves:Autores:Brea J., Castro M., Costa M., Filipe Miguel Areias, Loza M.I., Proença M.F.Fuentes:googlescopus