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European Journal of Medicinal Chemistry(1)
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Antifungal activity of a novel chromene dimer
ArticleAbstract: The activity on Aspergillus spp. growth and on ochratoxin A production of two novel chromene dimersPalabras claves:Antifungal compounds, Aspergillus spp., Chromenes, Ochratoxin AAutores:Abrunhosa L., Costa M., Filipe Miguel Areias, Proença M.F., Venâncio A.Fuentes:googlescopusA base-catalyzed cascade route to phenolic 6-cyanopurines via O -alkylformamidoximes
ArticleAbstract: N-[1,2-Dicyano-2-(hydroxyphenylideneamino)vinyl]-O-alkylformamidoximes were prepared from the reactiPalabras claves:amidoximes, Imidazoles, nitrogen heterocycles, phenols, purinesAutores:Filipe Miguel Areias, Proença M.F.Fuentes:googlescopusNew chromene scaffolds for adenosine A<inf>2A</inf> receptors: Synthesis, pharmacology and structure-activity relationships
ArticleAbstract: In silico screening of a collection of 1584 academic compounds identified a small molecule hit for tPalabras claves:Adenosine receptors, Chromene scaffolds, G protein-coupled receptors, Knoevenagel condensation, Structure-activity relationshipAutores:Brea J., Castro M., Costa M., Filipe Miguel Areias, Gregori-Puigjané E., Loza M.I., Mestres J., Proença M.F.Fuentes:googlescopusNew nitrogen compounds coupled to phenolic units with antioxidant and antifungal activities: Synthesis and structure-activity relationship
ArticleAbstract: A selection of 1-amino-2-arylidenamine-1,2-(dicyano)ethenes 3 was synthesized and cyclized to 2-arylPalabras claves:Antifungal activity, Antioxidant capacity, Imidazoles, MIC, PHENOLIC COMPOUNDS, Structureactivity relationshipAutores:Bettencourt A.P., Castro M., Coutinho O.P., Fernandes F., Filipe Miguel Areias, Proença M.F., Silva J.P., Sousa M.J.Fuentes:googlescopusOxidative stress protection by newly synthesized nitrogen compounds with pharmacological potential
ArticleAbstract: In this study we used new nitrogen compounds obtained by organic synthesis whose structure pbkp_rediPalabras claves:Antioxidants, Cell apoptosis, Lipid peroxidation, Nitrogen compounds, Oxidative StressAutores:Coutinho O.P., Filipe Miguel Areias, Proença M.F., Silva J.P.Fuentes:googlescopusIdentification of novel scaffolds from an original chemical library as potential antipsychotics
Conference ObjectAbstract: The ligand-based virtual screening of an original chemical library, using atypical antipsychotics asPalabras claves:5-HT 2A, Antipsychotic, drug design, Purine, serotonin receptors, Virtual ScreeningAutores:Brea J., Cadavid M.I., Carvalho M.A., Correia C., Filipe Miguel Areias, Gutiérrez-de-Terán H., Loza M.I., Proença M.F., Rodriguez D.Fuentes:googlescopusPhenolic imidazole derivatives with dual antioxidant/antifungal activity: Synthesis and structure-activity relationship
ArticleAbstract: Background: Previous publications show that the addition of a phenolic antioxidant to an antifungalPalabras claves:Antifungal activity, Antioxidant activity, Cáncer, Phenolic imidazoles, Phenolic purines, Structure-activity relationshipAutores:Bettencourt A.P., Castro M., Coutinho O.P., Fernandes F., Filipe Miguel Areias, Proença M.F., Silva J.P., Sousa M.J.Fuentes:googlescopusSynthesis of novel chromene scaffolds for adenosine receptors
ArticleAbstract: A one-pot procedure was developed for the synthesis of novel 3-[amino(methoxy)methylene]-2-oxo-3,4-dPalabras claves:Autores:Brea J., Castro M., Costa M., Filipe Miguel Areias, Loza M.I., Proença M.F.Fuentes:googlescopus