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Dietary bovine milk miRNAs transported in extracellular vesicles are partially stable during GI digestion, are bioavailable and reach target tissues but need a minimum dose to impact on gene expression
ArticleAbstract: PURPOSE: Extracellular RNAs are unstable and rapidly degraded unless protected. Bovine-milk extracelPalabras claves:exosomes, Extracellular vesicles, in vitro digestion, Milk miRNAs, Transcriptome, TransfectionAutores:Almudena García-Ruiz, Dávalos A., del Pozo-Acebo L., Gil-Zamorano J., Gómez-Coronado D., Hansen M.S., López de Las Hazas M.C., Mantilla-Escalante D.C., Marín F., Rasmussen J.T.Fuentes:scopusEating microRNAs: pharmacological opportunities for cross-kingdom regulation and implications in host gene and gut microbiota modulation
ReviewAbstract: Cross-kingdom communication via non-coding RNAs is a recent discovery. Exogenous microRNAs (exog-miRPalabras claves:cross species, cross-kingdom, diet, Digestion, exosomes, food safety, miRNAs, ncRNAAutores:Almudena García-Ruiz, Dávalos A., del Pozo-Acebo L., López de Las Hazas M.C., Margollés A.Fuentes:scopus