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scopus(5)
Novel 7-Chloro-(4-thioalkylquinoline) Derivatives: Synthesis and Antiproliferative Activity through Inducing Apoptosis and DNA/RNA Damage
ArticleAbstract: A series of 78 synthetic 7-chloro-(4-thioalkylquinoline) derivatives were investigated for cytotoxicPalabras claves:antiproliferative activity, cell cycle, DNA/RNA damage, Sulfanyl-Sulfinyl-Sulfonyl groups, synthesis of 4-thioalkylquinolineAutores:Bruno-Colmenarez J., Charris J.E., de Sanctis J.B., Deffieux D., Džubák P., Esteban Fernández-Moreira, Gurská S., Gutiérrez J.E., Hajdůch M., Hegira Ramírez, Mijares M.R., Pouységu L., Quideau S., Rodríguez M.A., Rojas L.B.Fuentes:scopusSynthesis and antimalarial and anticancer evaluation of 7-chlorquinoline-4-thiazoleacetic derivatives containing aryl hydrazide moieties
ArticleAbstract: Twelve 7-chloroquinoline derivatives were designed and synthesized using the principle of molecularPalabras claves:Antimalarial, Antiproliferative, apoptosis, hydrazides, quinoline, thiazolAutores:Celis C., Charris J.E., de Sanctis J.B., Esteban Fernandez, Hegira Ramírez, Martinez G.P., Mayora S., Mijares M.R., Rodrigues J.R.Fuentes:scopusSynthesis and biological activity of 2-[2-(7-chloroquinolin-4-ylthio)-4-methylthiazol-5-yl]-N-phenylacetamide derivatives as antimalarial and cytotoxic agents
ArticleAbstract: A novel series of 2-[2-(7-chloroquinolin-4-ylthio)-4-methylthiazol-5-yl]-N-phenylacetamide derivativPalabras claves:ANTICANCER, Antimalarial, plasmodium, quinoline, thiazoleacetic acidAutores:Charris J.E., de Sanctis J.B., Hegira Ramírez, Mijares M.R., Rodrigues J.R.Fuentes:scopusSynthesis and in silico ADME/Tox profiling studies of heterocyclic hybrids based on chloroquine scaffolds with potential antimalarial activity
ArticleAbstract: A series of heterocyclic chloroquine hybrids containing either a β-phenethylamine fragment or a 2-amPalabras claves:2-Aminoindane, Chloroquine, Hemozoin, MALARIA, β-PhenethylamineAutores:Ángel J.E., Charris J.E., Esteban Fernández-Moreira, Hegira Ramírez, Mijares M.R., Rodrigues J.R.Fuentes:scopusSynthesis, Leishmanicidal, Trypanocidal, Antiproliferative Assay and Apoptotic Induction of (2-Phenoxypyridin-3-yl)naphthalene-1(2H)-one Derivatives
ArticleAbstract: The coexistence of leishmaniasis, Chagas disease, and neoplasia in endemic areas has been extensivelPalabras claves:apoptosis, Cáncer, chalcone, leishmaniasis, TRYPANOSOMA CRUZIAutores:Ángel J.E., Blanco Z., Celis C., Charris J.E., de Sanctis J.B., Džubák P., Esteban Fernández-Moreira, García Y., Gurská S., Hajdůch M., Hegira Ramírez, Jhonny Correa-Abril, Martinez G.P., Mijares M.R., Mijoba A., Nahum Herrera, Serrano X., Yonathan De J. ParraFuentes:scopus