Mostrando 10 resultados de: 64
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Molecular Neurobiology(7)
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scopus(64)
Benzodiazepines and Related Drugs as a Risk Factor in Alzheimer's Disease Dementia
ArticleAbstract: Benzodiazepines (BZDs) and Z-drugs are compounds widely prescribed in medical practice due to theirPalabras claves:Alzheimer's disease, benzodiazepines, COGNITION, dementia, RISK FACTORSAutores:Antoni Camins, Auladell C., Bulló M., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusC-Jun N-Terminal Kinases in Alzheimer's Disease: A Possible Target for the Modulation of the Earliest Alterations
ReviewAbstract: Given the highly multifactorial origin of Alzheimer's disease (AD) neuropathology, disentangling andPalabras claves:Alzheimer's disease, Amyloid-β, axonal transport, hyperphosphorylated tau, JNK, synapse lossAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Parcerisas A., Verdaguer E., Zárate C.B.Fuentes:scopusAn overview of investigational antiapoptotic drugs with potential application for the treatment of neurodegenerative disorders
ReviewAbstract: Importance of the field: The increase in life expectancy in developed countries has given rise to sePalabras claves:Alzheimer's disease, apoptosis, Neuroprotective drugs, Parkinson's DiseaseAutores:Antoni Camins, Folch J., Junyent F., Pallás M., Sureda F.X., Verdaguer E., Zárate C.B.Fuentes:scopusAnti-inflammatory role of Leptin in glial cells through p38 MAPK pathway inhibition
ArticleAbstract: Background In the present work, we studied the modulatory effect of Leptin (Lep) against pro-inflammPalabras claves:Caspase-3, Cytochrome-c, Glial cells, iNOS, leptin, p38 MAPKAutores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., Martí A., Martínez N., Miguel Marin, Patraca I., Pedros I., Sureda F.X., Zárate C.B.Fuentes:scopusAntiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusAntiapoptotic effects of roscovitine on camptothecin-induced DNA damage in neuroblastoma cells
ArticleAbstract: In the present study dopaminergic neuroblastoma B65 cells were exposed to Camptothecin (CPT) (0.5-10Palabras claves:Ataxia telangiectasia mutated, camptothecin, cell cycle, RoscovitineAutores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Pizarro J.G., Verdaguer E., Zárate C.B.Fuentes:scopusA metabolic perspective of late onset Alzheimer's disease
ReviewAbstract: After decades of research, the molecular neuropathology of Alzheimer's disease (AD)is still one of tPalabras claves:Alzheimer's disease, c-Jun N-terminal kinase inhibitors, Insulin, Licochalcone A, neuroinflammation, Reticulum stress, Type 2 Diabetes mellitusAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Sanchez-Lopez E., Verdaguer E., Zárate C.B.Fuentes:scopusA single dose of pirfenidone attenuates neuronal loss and reduces lipid peroxidation after kainic acid-induced excitotoxicity in the pubescent rat hippocampus
ArticleAbstract: Systemic administration of kainic acid (KA) in rodents triggers limbic seizures following selectivePalabras claves:4-Hydroxynonenal (4-HNE), Kainic Acid Model, Neurodegeneration, neuroprotection, PirfenidoneAutores:Antoni Camins, Armendáriz-Borunda J., Bañuelos-Pineda J., Castro-Torres R.D., Chaparro-Huerta V., Flores-Soto M.E., Orozco-Suárez S.A., Zárate C.B.Fuentes:scopusDexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways
ArticleAbstract: The aim of the present study is to elucidate the neuronal pathways associated to NSAIDs causing a rePalabras claves:Alzheimer's disease, APPswe/PS1dE9, Dexibuprofen, hippocampus, insulin receptor, Memory impairment, Mitochondria, TauAutores:Antoni Camins, Auladell C., Busquets O., Ettcheto M., Folch J., García M.L., Olloquequi J., Pallás M., Pons L., Sanchez-Lopez E., Zárate C.B.Fuentes:scopusCorrection to: Peripheral and Central Effects of Memantine in a Mixed Preclinical Mice Model of Obesity and Familial Alzheimer’s Disease (Molecular Neurobiology, (2018), 55, 9, (7327-7339), 10.1007/s12035-018-0868-4)
OtherAbstract: The original version of this article unfortunately contained mistake. The authors found that Fig. 4.Palabras claves:Autores:Antoni Camins, Auladell C., Busquets O., Cabrera H., Carrera M.V., Carro E., Casadesús G., Ettcheto M., Folch J., García M.L., Gómez-Mínguez Y., Sanchez-Lopez E., Zárate C.B.Fuentes:scopus