Mostrando 10 resultados de: 64
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scopus(64)
HIF-1α expression in the hippocampus and peripheral macrophages after glutamate-induced excitotoxicity
ArticleAbstract: Hypoxia-inducible factor-1 alpha (HIF-1α) is a master transcription factor that regulates the responPalabras claves:EPO, Excitotoxicity, HIF-1 alpha, hippocampus, Macrophages, VEGFAutores:Antoni Camins, Armendáriz-Borunda J., Chaparro-Huerta V., Flores-Soto M.E., Gudiño-Cabrera G., Pallás M., Rivera-Cervantes M.C., Torres-Mendoza B.M., Vázquez-Valls E., Zárate C.B.Fuentes:scopusHigh-fat diet-induced deregulation of hippocampal insulin signaling and mitochondrial homeostasis deficiences contribute to Alzheimer disease pathology in rodents
ArticleAbstract: Global obesity is a pandemic status, estimated to affect over 2 billion people, that has resulted inPalabras claves:Alzheimer disease, APPswe/PS1dE9, hippocampus, insulin receptor, Mitochondria, TauAutores:Antoni Camins, Artiach G., Barroso E., Carro E., Casadesús G., Ferrer I., Folch J., Pallás M., Pedros I., Petrov D., Sureda F.X., Vázquez-Carrera M., Zárate C.B.Fuentes:scopusEpigallocatechin-3-Gallate (EGCG) Improves Cognitive Deficits Aggravated by an Obesogenic Diet Through Modulation of Unfolded Protein Response in APPswe/PS1dE9 Mice
ArticleAbstract: Epigallocatechin-3-gallate (EGCG), a catechin found in green tea, has been previously investigated fPalabras claves:APPswe/PS1dE9 mice, Cognitive deficits, Epigallocatechin-3-gallate, hippocampus, obesity, unfolded protein responseAutores:Antoni Camins, Auladell C., Busquets O., Cano A., Castro-Torres R.D., Ettcheto M., Folch J., García M.L., Manzine P.R., Olloquequi J., Verdaguer E., Zárate C.B.Fuentes:scopusEvaluation of hypoxia inducible factor expression in inflammatory and neurodegenerative brain models
ArticleAbstract: The neuroinflammatory process is thought to contribute to the progression of neurological disordersPalabras claves:Alzheimer's, apoptosis, APP/PS1, c-Jun, HIF-1αAutores:Antoni Camins, Auladell C., Brox S., de la Torre A.V., De Lemos M.L., Folch J., Lazarowski A., Pallás M., Petrov D., Zárate C.B.Fuentes:scopusEvaluation of neuropathological effects of a high-fat diet in a presymptomatic Alzheimer's disease stage in APP/PS1 mice
ArticleAbstract: Alzheimer's disease (AD) is currently an incurable aging-related neurodegenerative disorder. RecentPalabras claves:Alzheimer's disease, APPswe/PS1dE9, hippocampus, insulin receptor, Mitochondria, TauAutores:Alva N., Antoni Camins, Auladell C., Carbonell T., Ettcheto M., Folch J., Pallás M., Pedros I., Petrov D., Zárate C.B.Fuentes:scopusGSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons
ArticleAbstract: In the present study, we evaluated the effects of roscovitine (Rosco) and flavopiridol (Flavo), bothPalabras claves:apoptosis, Cerebellar granular cells, flavopiridol, GSK3β, RoscovitineAutores:Antoni Camins, Auladell C., de la Torre A.V., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusGene expression profile in JNK3 null mice: A novel specific activation of the PI3K/AKT pathway
ArticleAbstract: JNK3 is mainly expressed in the CNS and it plays a crucial role in neuronal death in several neurodePalabras claves:Akt, Gene profiling, JNK, Neurodegeneration, neuroprotection, PI3KAutores:Antoni Camins, Auladell C., De Lemos M.L., Ferrer I., Folch J., Junyent F., Ortuo-Sahagún D., Pallás M., Romero R., Verdaguer E., Zárate C.B.Fuentes:scopusDendritic spine abnormalities in hippocampal CA1 pyramidal neurons underlying memory deficits in the SAMP8 mouse model of Alzheimer's disease
ArticleAbstract: SAMP8 is a strain of mice with accelerated senescence. These mice have recently been the focus of atPalabras claves:Alzheimer's disease, Dendrites, Learning, MEMORY, object recognition test, SAMP8, Senescence, synaptophysinAutores:Antoni Camins, Bayod S., Del Valle J., González-Burgos I., Pallás M., Velázquez-Zamora D.A., Zárate C.B.Fuentes:scopusC-Jun N-Terminal Kinases in Alzheimer's Disease: A Possible Target for the Modulation of the Earliest Alterations
ReviewAbstract: Given the highly multifactorial origin of Alzheimer's disease (AD) neuropathology, disentangling andPalabras claves:Alzheimer's disease, Amyloid-β, axonal transport, hyperphosphorylated tau, JNK, synapse lossAutores:Antoni Camins, Auladell C., Busquets O., Castro-Torres R.D., Ettcheto M., Parcerisas A., Verdaguer E., Zárate C.B.Fuentes:scopusCell cycle control by ataxia telangiectasia mutated protein through regulating retinoblastoma protein phosphorylation
Book PartAbstract: The ability of cells to maintain their genomic integrity is essential to the prevention of cancer dePalabras claves:Autores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Pizarro J.G., Verdaguer E., Zárate C.B.Fuentes:scopus