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Synthesis and in silico ADME/Tox profiling studies of heterocyclic hybrids based on chloroquine scaffolds with potential antimalarial activity
ArticleAbstract: A series of heterocyclic chloroquine hybrids containing either a β-phenethylamine fragment or a 2-amPalabras claves:2-Aminoindane, Chloroquine, Hemozoin, MALARIA, β-PhenethylamineAutores:Ángel J.E., Charris J.E., Esteban Fernández-Moreira, Hegira Ramírez, Mijares M.R., Rodrigues J.R.Fuentes:scopusSynthesis, Leishmanicidal, Trypanocidal, Antiproliferative Assay and Apoptotic Induction of (2-Phenoxypyridin-3-yl)naphthalene-1(2H)-one Derivatives
ArticleAbstract: The coexistence of leishmaniasis, Chagas disease, and neoplasia in endemic areas has been extensivelPalabras claves:apoptosis, Cáncer, chalcone, leishmaniasis, TRYPANOSOMA CRUZIAutores:Ángel J.E., Blanco Z., Celis C., Charris J.E., de Sanctis J.B., Džubák P., Esteban Fernández-Moreira, García Y., Gurská S., Hajdůch M., Hegira Ramírez, Jhonny Correa-Abril, Martinez G.P., Mijares M.R., Mijoba A., Nahum Herrera, Serrano X., Yonathan De J. ParraFuentes:scopus