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Article(5)
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Cancer Chemotherapy and Pharmacology(1)
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scopus(5)
Cytotoxic activity of seco-entkaurenes from Croton caracasana on human cancer cell lines
ArticleAbstract: In the course of searching for bioactive compounds from Croton species from Venezuela, two seco-entkPalabras claves:Croton caracasana, Cytotoxic, euphorbiaceae, seco-entkaurenesAutores:Alírica Isabel Suárez, Arvelo F.A., Chavez K., Compagnone R.S., de Sanctis J.B., Mateu E., Mijares M.R., Muñoz A., Sojo F.J.Fuentes:scopusCytotoxic and proapoptotic activity of ent-16β-17α- dihydroxykaurane on human mammary carcinoma cell line MCF-7
ArticleAbstract: Here we describe the cytotoxic and proapoptotic effect of an ent-kaurane (ent-16β-17α-dihydroxykauraPalabras claves:Anticancer agents, apoptosis, BCL2, Cytotoxic activity, Ent-kaurane, Telomerase activityAutores:Alírica Isabel Suárez, Arvelo F.A., Compagnone R.S., Galindo-Castro I., Luis Ramírez J., Mendoza R., Morales A., Pérez P.Fuentes:scopusCytotoxic effects of fisturalin-3 and 11-Deoxyfisturalin-3 on Jurkat and U937 cell lines
ArticleAbstract: Background. Fisturalines are bromotyrosine compounds isolated from marine sponges. Previous studiesPalabras claves:11-deoxyfistularin-3, Aplysina fistularis, Bromotyrosine, Cáncer, Fistularin-3, Leukemia, quercetinAutores:Alírica Isabel Suárez, Avila R., Barroeta A., Chirinos P., Compagnone R.S., de Sanctis J.B., Martinez G.P., Mijares M.R., Ochoa M.Fuentes:scopusCaracasine acid, an ent-3,4-seco-kaurene, promotes apoptosis and cell differentiation through NFkB signal pathway inhibition in leukemia cells.
ArticleAbstract: Caracasine acid (CA) is an ent-3,4-seco-kaurene isolated from the plant Croton micans. Decreased canPalabras claves:Annexin-V, apoptosis, Cáncer, Caracasine acid, Croton, Kaurene compounds, Leukemia, NF-κBAutores:Alírica Isabel Suárez, Chavez K., Chirinos P., Compagnone R.S., de Sanctis J.B., Martinez G.P., Mijares M.R.Fuentes:scopusThe marine sponge toxin agelasine B increases the intracellular Ca <sup>2+</sup> concentration and induces apoptosis in human breast cancer cells (MCF-7)
ArticleAbstract: Purpose: In search for new drugs derived from natural products for the possible treatment of cancer,Palabras claves:Agelasine B, calcium, Natural products, SERCA, ThapsigarginAutores:Alírica Isabel Suárez, Arvelo F.A., Benaím G., Chirino P., Colman L., Compagnone R.S., de Sanctis J.B., Dipolo R., Felibertt P., Galindo-Castro I., Mayora A., Pimentel A.A., Rojas H., Silva M.L., Sojo F.J.Fuentes:scopus