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CYP2C9 Promoter Variable Number Tandem Repeat Polymorphism in a Dominican Population: Exploring Differences with Genetic Ancestry
ArticleAbstract: A variable number tandem repeat polymorphism has been described in the CYP2C9 promoter (pVNTR) withPalabras claves:Ancestry, CYP2C9, linkage disequilibrium, pVNTRAutores:Adrián LLerena, Carla González de la Cruz, Dorado P., Ernesto Rodríguez, Guevara-García M., Penãs-Lledó E.M., Rodrigues-Soares F.Fuentes:scopusThe Frequency of DPYD c.557A>G in the Dominican Population and Its Association with African Ancestry
ArticleAbstract: Background/Objectives: Genetic polymorphism of the dihydropyrimidine dehydrogenase gene (DPYD) is rePalabras claves:African ancestry, Cancer, DPYD, fluoropyrimidines, pharmacogeneticsAutores:Adrián LLerena, Caíque Manóchio, Carla González de la Cruz, Dorado P., Ernesto Rodríguez, Guevara-García M., Penãs-Lledó E.M., Rodrigues-Soares F.Fuentes:scopusRelevance of the c.557A>G variant for the implementation of DPYD pharmacogenetics in populations with Afro-Latin American ancestry
ReviewAbstract: Fluoropyrimidines are chemotherapy treatments widely used in chemotherapeutic regimens for differentPalabras claves:Afro-Latin Americans, c.557A>G, DPYD, fluoropyrimidinesAutores:Adrián LLerena, Caíque Manóchio, Carla González De La Cruz, Dorado P., Ernesto Rodríguez, Guevara-García M., Penãs-Lledó E.M., Rodrigues-Soares F.Fuentes:scopus