Documentos de Perez G. | REDI

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Área temáticas: "Farmacología y terapéutica"

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FEBS Letters(1)

Protein Engineering, Design and Selection(1)

Área temáticas

Fisiología humana(1)

Fisiología y materias afines(1)

Microorganismos, hongos y algas(1)

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Enzymatic processing(1)

Proinsulin folding(1)

Recombinant insulin(1)

Expression and folding of an interleukin-2-proinsulin fusion protein and its conversion into insulin by a single step enzymatic removal of the C-peptide and the N-terminal fused sequence

Abstract: We report the expression in E. coli of a proinsulin fusion protein carrying a modified interleukin-2

Palabras claves:

Enzymatic processing, Proinsulin folding, Recombinant insulin

Besada-Pérez V., Castellanos‐Serra L., Eugenio Hardy, Falcón-Cama V., Fernandez C., Gonzalez M., Herrera L., Perez G., Santiago Nelson Vispo, Santos-Savio A., Silva A., Ubieta R.

Expression of il-2/proinsulin fusion protein: Folding of the fusion protein and conversion into insulin by a one step removal of c-peptide and leader sequence

Palabras claves:

Besada-Pérez V., Castellanos L.R., Estrada R., Eugenio Hardy, Fernandez C., Gonzalez M., Herrera L., Jimenez V., Perez G., Santiago Nelson Vispo, Silva A., Ubieta R.