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A TOPological Sub-structural Molecular Design (TOPS-MODE)-QSAR approach for modeling the antiproliferative activity against murine leukemia tumor cell line (L1210)
ArticleAbstract: Lately, Quantitative Structure-Activity Relationship (QSAR) studies have been afar used to predict aPalabras claves:anticancer activity, Indolcarbazole, Leukemia antitumor agents, RebeccamycinAutores:García-Mera X., Molina-Ruiz R., Natalia Dias Soeiro Cordeiro M., Perez González M., Rodríguez-Borges J.E., Saíz-Urra L., Yunierkis Perez-CastilloFuentes:googlescopusAn alignment-free approach for eukaryotic ITS2 annotation and phylogenetic inference
ArticleAbstract: The ITS2 gene class shows a high sequence divergence among its members that have complicated its annPalabras claves:Autores:Agüero-Chapin G., Aminael Sánchez-Rodríguez, Antunes A., Hidalgo-Yanes P.I., Marchal K., Molina-Ruiz R., Vasconcelos V., Yunierkis Perez-CastilloFuentes:googlescopusDISTATIS: A Promising Framework to Integrate Distance Matrices in Molecular Phylogenetics
ArticleAbstract: BACKGROUND: Molecular phylogenetic algorithms frequently disagree with the approaches considering rePalabras claves:Alignment-free, Ascospore morphology, DISTATIS, ITS2, mating strategy, phylogeneticsAutores:Agüero-Chapin G., Aminael Sánchez-Rodríguez, Antunes A., Molina-Ruiz R., Oscar Vivanco-Galván, Vivanco-Galván O., Yuliana Jiménez-GaonaFuentes:googlescopusDesirability-based methods of multiobjective optimization and ranking for global QSAR studies. Filtering safe and potent drug candidates from combinatorial libraries
ArticleAbstract: Up to now, very few applications of multiobjective optimization (MOOP) techniques to quantitative stPalabras claves:Autores:Borges F., Cagide Fajin J.L., Cañizares-Carmenate Y., Dominguez E.R., Maykel Cruz-Monteagudo, Molina-Ruiz R., Morell Pérez C., Natalia Dias Soeiro Cordeiro M.Fuentes:scopusExploring the Adenylation Domain Repertoire of Nonribosomal Peptide Synthetases Using an Ensemble of Sequence-Search Methods
ArticleAbstract: The introduction of two-dimension (2D) graphs and their numerical characterization for comparative aPalabras claves:Autores:Agüero-Chapin G., Aminael Sánchez-Rodríguez, Antunes A., de la Riva G.A., Maldonado E., Molina-Ruiz R., Vasconcelos V.Fuentes:googlescopusNon-linear models based on simple topological indices to identify RNase III protein members
ArticleAbstract: Alignment-free classifiers are especially useful in the functional classification of protein classesPalabras claves:Alignment-free models, artificial neural networks, Clustering, Decision tree models, Spectral momentsAutores:Agüero-Chapin G., Aminael Sánchez-Rodríguez, Antunes A., de la Riva G.A., Molina-Ruiz R., Pérez-Machado G., Vasconcelos V.Fuentes:googlescopusTI2BioP: Topological Indices to BioPolymers. Its practical use to unravel cryptic bacteriocin-like domains
ArticleAbstract: Bacteriocins are proteinaceous toxins produced and exported by both gram-negative and gram-positivePalabras claves:Alignment methods, Artificial secondary structure, Bacteriocin, Spectral moments, topological indicesAutores:Agüero-Chapin G., Antunes A., Molina-Ruiz R., Morales-Helguera A., Pérez-Machado G., Vasconcelos V., Yunierkis Perez-CastilloFuentes:googlescopus