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Characterization of the A<inf>2A</inf>R-D<inf>2</inf>R interface: Focus on the role of the C-terminal tail and the transmembrane helices
ArticleAbstract: A single serine point mutation (S374A) in the adenosine A2A receptor (A2AR) C-terminal tail reducesPalabras claves:Adenosine A receptor 2A, Dopamine D receptor 2, G protein coupled receptors, Heteromerization, Protein-protein interaction, Transmembrane segmentsAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Corrales F., Flajolet M., Frankowska M., Fuxe K., Gómez-Soler M., Heintz N., Marcellino D., Narváez M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusAgonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family
ArticleAbstract: Fibroblast growth factor receptor 1 (FGFR1) is known to be activated by homodimerization in the presPalabras claves:BRET, FGFR1, Fibroblast growth factors, Homodimerization, MAPKAutores:Agnati L.F., Belluardo N., Borroto-Escuela D.O., Ciruela F., Fuxe K., Mudó G., Narváez M., Pérez-Alea M., Tarakanov A.O., W. Romero-FernandezFuentes:scopusDopamine D2 and 5-hydroxytryptamine 5-HT<inf>2A</inf> receptors assemble into functionally interacting heteromers
ArticleAbstract: In view of the co-distribution of dopamine D2LR and 5-hydroxytryptamine 5-HT2A receptors (D2LR and 5Palabras claves:allosteric modulation, Dopamine D R receptor 2, G protein-coupled receptors, Heteromerization, protein-protein interactions, Serotonin 5-HT receptor 2AAutores:Agnati L.F., Borroto-Escuela D.O., Ciruela F., Fuxe K., Marcellino D., Tarakanov A.O., W. Romero-FernandezFuentes:scopusDopamine D2 and D4 receptor heteromerization and its allosteric receptor-receptor interactions
ArticleAbstract: Dopamine D2 and D4 receptors partially codistribute in the dorsal striatum and appear to play a fundPalabras claves:allosteric modulation, Dopamine D R receptor 2, Dopamine D R receptor 4, G protein-coupled receptors, Heteromerization, Protein-protein interactions.Autores:Agnati L.F., Borroto-Escuela D.O., Craenenbroeck K.V., Fuxe K., Guidolin D., Haegeman G., Rivera A., Tarakanov A.O., W. Romero-Fernandez, Woods A.S.Fuentes:scopusDopamine D2 receptor signaling dynamics of dopamine D2-neurotensin 1 receptor heteromers
ArticleAbstract: Biochemical, histochemical and coimmunoprecipitation experiments have indicated the existence of antPalabras claves:allosteric modulation, Dopamine D R receptor 2, G protein-coupled receptors, Heteromerization, Neurotensin 1 receptor, protein-protein interactionsAutores:Agnati L.F., Borroto-Escuela D.O., Brito I., Corrales F., Ferraro L., Fuxe K., Narváez M., Ravani A., Tanganelli S., Tarakanov A.O., W. Romero-FernandezFuentes:scopusHallucinogenic 5-HT2AR agonists LSD and DOI enhance dopamine D2R protomer recognition and signaling of D2-5-HT2A heteroreceptor complexes
ArticleAbstract: Dopamine D2LR-serotonin 5-HT2AR heteromers were demonstrated in HEK293 cells after cotransfection ofPalabras claves:2,5-Dimethoxy-4-iodoamphetamine, allosteric modulation, Antipsychotic drugs, dopamine D2 receptor, G-protein-coupled receptors, Heterodimerization, Heteroreceptor complexes, Lysergic acid diethylamide, Receptor-receptor interactions, Serotonin 5-HT2A receptorAutores:Agnati L.F., Borroto-Escuela D.O., Fuxe K., Narváez M., Oflijan J., W. Romero-FernandezFuentes:scopus