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Development of anticancer drugs based on the hallmarks of tumor cells
ReviewAbstract: Cancer remains a public health problem with a high unmet medical demand. However, in recent decades,Palabras claves:Cáncer, Cancer cell hallmarks, drug designAutores:J. Romero Benavides, Juan Carlos Romero-Benavides, N. Bailon Moscoso, Natalia Bailon-Moscoso, Ostrosky-Wegman P.Fuentes:googlerraaescopusCytotoxic Property of Grias neuberthii Extract on Human Colon Cancer Cells: A Crucial Role of Autophagy
ArticleAbstract: Traditional herbal medicine has become an important alternative in the treatment of various cancer tPalabras claves:Autores:Alírica Isabel Suárez, Jimmy Samaniego-Romero, Juan Carlos Romero-Benavides, Luis Miguel Guamán Ortíz, Natalia Bailon-Moscoso, Ortiz-Diaz K., Paola Castillo-Veintimilla, Stephania Torres-AguilarFuentes:scopusArgentatin B derivatives induce cell cycle arrest and DNA damage in human colon cancer cells through p73/p53 regulation
ArticleAbstract: The unique etiology of cancer requires a multidimensional approach for its treatment, control, and pPalabras claves:Argentatin B, cell cycle arrest, Colon cancer, genotoxicity, P53, p73Autores:Gabriela J. González-Arévalo, Henrry Cabrera, Javier Villacís, Juan Carlos Romero-Benavides, Maria Isabel Ramirez Orellana, Martínez-Vázquez M., Natalia Bailon-Moscoso, Parra-Delgado H., Ratovitski E.A., Ruth Cueva, Zentella-Dehesa A.Fuentes:googlescopusEstudio fitoquímico y evaluación antineoplásica y antihelmíntica de la especie Echinopsis pachanoi
Master ThesisAbstract: De Echinopsis pachanoi se obtuvo el extracto en diclorometano:metanol y mediante partición líquido-lPalabras claves:Citotoxicidad, Echinopsis pachanoi, Éster metílico del ácido linolénico, Magíster en Química Aplicada- Tesis y disertaciones académicas, Strongyloides venezuelensisAutores:Juan Carlos Romero-Benavides, Paola Maribel Castillo VeintimillaFuentes:rraaeNatural compounds as modulators of cell cycle arrest: Application for anticancer chemotherapies
ReviewAbstract: Natural compounds from various plants, microorganisms and marine species play an important role in tPalabras claves:Cáncer, cell cycle arrest, MITÓSIS, Natural compoundsAutores:Gabriela Cevallos-Solórzano, Juan Carlos Romero-Benavides, Maria Isabel Ramirez Orellana, Natalia Bailon-MoscosoFuentes:scopusMedicinal plants of Ecuador: A review of plants with anticancer potential and their chemical composition
ReviewAbstract: Ecuador is well known for its biodiversity and its ancient richness. This review provides an overviePalabras claves:ANTICANCER, ECUADOR, ethnobotany, Ethnomedicine, PlantAutores:Fani Tinitana-Imaicela, Juan Carlos Romero-Benavides, Natalia Bailon-Moscoso, Ostrosky-Wegman P.Fuentes:googlescopusProducción Obtención de extractos, aislamiento y caracterización de metabolitos secundarios de Silybum marianum L. Gaertn con posible actividad antitumoral
Bachelor ThesisAbstract: La especie Silybum marianum (L.) Gaertn fue recolectada en el barrio Los Geranios, de la ciudad de LPalabras claves:Estudio fitoquímico, Ingeniero químico – Tesis y disertaciones académicas, Plantas – ExtractosAutores:Johanna Maribel Castillo Jaramillo, Juan Carlos Romero-BenavidesFuentes:rraaeSynthesis of 4,4′-(arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ols) and evaluation of their antioxidant and anticancer activities
ArticleAbstract: Background: Pyrazoles have attracted particular attention due to the diverse biological activities aPalabras claves:4,4ʹ-(arylmethylene)bis(1H-pyrazol-5-ols), antioxidant, apoptosis, AutophagyAutores:Jorge Hebkp_redia-Moya, José Eduardo Cadena-Cruz, Juan Carlos Romero-Benavides, Kevin E. Murillo-Sotomayor, Luis Guaman, Luis Miguel Guamán Ortíz, Nadia V. Ortiz-Guamán, Natalia Bailon-MoscosoFuentes:googlescopus