CTLA4 message reflects pathway disruption in monogenic disorders and under therapeutic blockade

Review

Abstract: CTLA-4 is essential for immune tolerance. Heterozygous CTLA4 mutations cause immune dysregulation ev

Palabras claves:

CTLA4, immunotherapy, Ipilimumab, LRBA, mRNA

Autores:

Baxter R.M., Dutmer C.M., Hsieh E.W.Y., Jordan M.B., Josselyn E. Garcia-Perez, Kong D.S., McCarter M., Routes J.M., Tobin R., Verbsky J.

Fuentes:

scopus