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Combined Point-of-Care Nucleic Acid and Antibody Testing for SARS-CoV-2 following Emergence of D614G Spike Variant
ArticleAbstract: Rapid COVID-19 diagnosis in the hospital is essential, although this is complicated by 30%–50% of noPalabras claves:covid-19, D614G, point of care testing, rapid diagnoses, SARS-COV-2Autores:Abeseabe R., Allain J.P., Amoroso G., Assennato S.M., Baker S., Barmpounakis P., Bates A., Bergamaschi L., Bermperi A., Blake E., Bousfield R., Boyle A., Bradley J.R., Briggs J.A.G., Brown N., Bucke A., Bundi P., Calder J., Canna L., Chapman D., Chatterjee K., Chiu E., Ciazynska K.A., Clark S., Collier D.A., Crucusio C., Curran M.D., Davidson F., de Jesus R., Demeris N., Domingo J., Dougan G., Elmer A., Emma Jones, Enoch D., Fabiculana M., Foster E., Frost S., Gkrania-Klotsas E., Goel N., Goodfellow I.G., Gupta R.K., Hardwick S., Hardy R., Harris J., Hewitt S., Hosmillo M., James L.C., Jose S., Kennet J., Kiss L., Knock H., Kourampa E., Kourampa J., Lehner P.J., Lyons P.A., Matheson N.J., Meadows A., Mendoza V., Meng B., Mescia F., Mlcochova P., Mynott L., Nathan J.A., O'Brien C., Overhill A., Palmar S., Pasquale C., Perales M., Phillips D., Price J., Ramenatte N., Rastall R., Ribeiro C., Ritchie A., Rowlands J., Rundell V., Saunders C., Shaw A., Sipple J., Skells R., Smith K.G.C., Sparkes D., Temperton N.J., Tordesillas H., Toshner M., Vallier A.L., Vargas P., Vergese B., Vicente I., Watson L., Weekes M.P., Williams A., Wilson M., Worsley J., Xiong X., Zerrudo J.A., Zhang H.Fuentes:scopusLongitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease
ArticleAbstract: The kinetics of the immune changes in COVID-19 across severity groups have not been rigorously assesPalabras claves:bystander CD8+ T cell, complement, covid-19, immune pathology, INTERFERÓN, recovery, SARS-COV-2, Systemic inflammation, TNF-αAutores:Allison J., Ansaripour A., Baker S., Bergamaschi L., Betancourt A., Bong S.H., Bower G., Bradley J.R., Bucke A., Bullman B., Bunclark K., Butcher H., Calder J., Calero-Nieto F.J., Canna L., Caputo D., Clapham-Riley D., Cossetti C., Coudert J.D., de Bie E.M.D.D., de Sa A., Dewhurst E., di Stefano G., Doffinger R., Domingo J., Dougan G., Dunmore B.J., Elmer A., Emma Jones, Epping M., Fahey C., Fawke S., Fuller S., Furlong A., Gerber P.P., Gleadall N., Goodfellow I.G., Göttgens B., Graf S., Graves B., Gray J., Grenfell R., Gupta R.K., Hanson A.L., Harris J., Hess C., Hewitt S., Hinch A., Hodgson J., Holmes E., Hosmillo M., Huang C., Huhn O., Hunter K., Ivers T., Jackson S., Jarvis I., Jose S., Josipovic M., Kasanicki M., Kennet J., Kingston N., Kotagiri P., Kourampa J., Laurenti E., Le Gresley E., Legchenko E., Lehner P.J., Lewis D., Linger R., Lyons P.A., Mackay M., Marioni J.C., Marsden J., Martin J., Matara C., Matheson N.J., Meadows A., Meloy S., Mende N., Mescia F., Michael A., Michel R., Morgan M.D., Muldoon F., Mwaura L., Nice F., Nicholson J.K., Petrunkina A.M., Richardson S., Ruffieux H., Saunders C., Smith K.G.C., Thaventhiran J.E.D., Toonen E.J.M., Toshner M., Turner L., Weekes M.P., Wills M.R.Fuentes:scopusSARS-CoV-2 spike N-terminal domain modulates TMPRSS2-dependent viral entry and fusogenicity
ArticleAbstract: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike N-terminal domain (NTD) remaiPalabras claves:CP: Microbiology, DELTA, entry, fusogenicity, NTD, Omicron, Organoid, SARS-COV-2, spike, TMPRSS2Autores:Allison J., Baker S., Betancourt A., Bower G., Bucke A., Bullman B., Bunclark K., Butcher H., Calder J., Canna L., Caputo D., Choi J., Clapham-Riley D., Cossetti C., Datir R.P., de Bie E.M.D.D., de Sa A., Dewhurst E., Domingo J., Dougan G., Dunmore B.J., Elmer A., Emma Jones, Epping M., Fawke S., Fuller S., Furlong A., Gleadall N., Graf S., Graves B., Gray J., Grenfell R., Harris J., Hess C., Hewitt S., Hinch A., Hodgson J., Huang C., Hunter K., Ivers T., Jackson S., Jarvis I., Jose S., Josipovic M., Kennet J., Kingston N., Kourampa J., Krishna B., Le Gresley E., Legchenko E., Lehner P.J., Linger R., Lyons P.A., Mackay M., Martin J., Matara C., Matheson N.J., Maxwell P., Meadows A., Meloy S., Meng B., Mescia F., Muldoon F., Nice F., O'Brien C., O'Donnell C., Omarjee O., Ovington N., Owehand W.H., Papadia S., Perera M., Phelan I., Pointon L., Potts M., Price J., Publico C., Rastall R., Ribeiro C., Richoz N., Romashova V., Rowlands J., Ruffolo V., Saunders C., Shaw A., Shih J., Stark H., Stefanucci L., Strezlecki M., Summers C., Sutcliffe R., Thaventhiran J.E.D., Tilly T., Tong Z., Tordesillas H., Toshner M., Treacy C., Turner L., Weekes M.P., Wood J., Wylot M.Fuentes:scopus