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Complexation of daclatasvir by single isomer methylated β-cyclodextrins studied by capillary electrophoresis, NMR spectroscopy and mass spectrometry
ArticleAbstract: In capillary electrophoresis an enantioseparation of daclatasvir (DCV) was observed in case of heptaPalabras claves:capillary electrophoresis, Complex stoichiometry, Complex structure, Cyclodextrin-analyte complexation, Mass spectrometry, nuclear magnetic resonance spectroscopyAutores:Antonio Salgado, Benkovics G., Chankvetadze B., Krait S., Malanga M., Naumann L., Neusüß C., Peluso P., Scriba G.K.E., Sohajda T.Fuentes:scopusStructural characterization of methyl-β-cyclodextrins by high-performance liquid chromatography and nuclear magnetic resonance spectroscopy and effect of their isomeric composition on the capillary electrophoresis enantioseparation of daclatasvir
ArticleAbstract: The separation of daclatasvir and its R,R,R,R-enantiomer was studied by capillary electrophoresis usPalabras claves:capillary electrophoresis, Cyclodextrin isomers, Degree of substitution, enantiomer migration order, Enantioseparation, Methyl-β-cyclodextrinAutores:Antonio Salgado, Benkovics G., Chankvetadze B., Krait S., Malanga M., Scriba G.K.E., Sohajda T., Szakály P.S.Fuentes:scopus