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Anti Cancer Agents in Medicinal Chemistry(2)
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European Journal of Pharmacology(1)
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Synthesis and antimalarial and anticancer evaluation of 7-chlorquinoline-4-thiazoleacetic derivatives containing aryl hydrazide moieties
ArticleAbstract: Twelve 7-chloroquinoline derivatives were designed and synthesized using the principle of molecularPalabras claves:Antimalarial, Antiproliferative, apoptosis, hydrazides, quinoline, thiazolAutores:Celis C., Charris J.E., de Sanctis J.B., Esteban Fernandez, Esteban Fernández-Moreira, Hegira Ramírez, Martinez G.P., Mayora S., Mijares M.R., Rodrigues J.R.Fuentes:scopusSynthesis, Leishmanicidal, Trypanocidal, Antiproliferative Assay and Apoptotic Induction of (2-Phenoxypyridin-3-yl)naphthalene-1(2H)-one Derivatives
ArticleAbstract: The coexistence of leishmaniasis, Chagas disease, and neoplasia in endemic areas has been extensivelPalabras claves:apoptosis, Cancer, chalcone, leishmaniasis, TRYPANOSOMA CRUZIAutores:Ángel J.E., Blanco Z., Celis C., Charris J.E., Correa J., de Sanctis J.B., Džubák P., Esteban Fernández-Moreira, García Y., Gurská S., Hajdůch M., Hegira Ramírez, Jhonny Correa-Abril, Martinez G.P., Mijares M.R., Mijoba A., Nahum Herrera, Serrano X., Serrano-Martín X., Yonathan De J. Parra, Yonathan J. ParraFuentes:scopusCytotoxic effects of fisturalin-3 and 11-Deoxyfisturalin-3 on Jurkat and U937 cell lines
ArticleAbstract: Background. Fisturalines are bromotyrosine compounds isolated from marine sponges. Previous studiesPalabras claves:11-deoxyfistularin-3, Aplysina fistularis, Bromotyrosine, Cancer, Fistularin-3, Leukemia, quercetinAutores:Alírica Isabel Suárez, Avila R., Barroeta A., Chirinos P., Compagnone R.S., de Sanctis J.B., Martinez G.P., Mijares M.R., Ochoa M.Fuentes:scopusCaracasine acid, an ent-3,4-seco-kaurene, promotes apoptosis and cell differentiation through NFkB signal pathway inhibition in leukemia cells.
ArticleAbstract: Caracasine acid (CA) is an ent-3,4-seco-kaurene isolated from the plant Croton micans. Decreased canPalabras claves:Annexin V, apoptosis, Cancer, Caracasine acid, Croton, Kaurene compounds, Leukemia, NF-κBAutores:Alírica Isabel Suárez, Chavez K., Chirinos P., Compagnone R.S., de Sanctis J.B., Martinez G.P., Mijares M.R.Fuentes:scopusCaracasine, An ent-kaurane Diterpene with Proapoptotic and Pro-differentiator Activity in Human Leukaemia Cell Lines
ArticleAbstract: Background: Kaurane-type diterpenoids, obtained from various natural sources, have shown many biologPalabras claves:apoptosis, Caracasine, Caracasine acid, Caspases, cell cycle, Differentiation, kaurane-type diterpenoids, NF-κBAutores:Alírica Isabel Suárez, Chavez K., Chirinos P., Compagnone R.S., de Sanctis J.B., Martinez G.P., Mijares M.R.Fuentes:scopusMolecular Mechanisms of Chloroquine and Hydroxychloroquine used in Cancer Therapy
ReviewAbstract: Tumour relapse, chemotherapy resistance, and metastasis continue to be unsolved issues in cancer thePalabras claves:apoptosis, chemotherapy, Chloroquine, Hydroxychloroquine, metastasis, Non-small cell lung cancer, repurposing drugs in oncologyAutores:Blanco Z., Charris J.E., de Sanctis J.B., Hegira Ramírez, Martinez G.P., Mijares M.R.Fuentes:scopus