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scopus(22)
Clustered granules present in the hippocampus of aged mice result from a degenerative process affecting astrocytes and their surrounding neuropil
ArticleAbstract: Clusters of pathological granular structures appear and progressively increase in number with age inPalabras claves:aging, Astrocyte, Granules, hippocampus, Neo-epitope, Periodic acid-Schiff, SAMP8Autores:Antoni Camins, Cabezón I., Liberski P.P., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusBlood-brain barrier disruption in the striatum of rats treated with 3-nitropropionic acid
ArticleAbstract: 3-Nitropropionic acid (3-NPA) is a natural toxin that is used to induce models of Huntington's diseaPalabras claves:3-nitropropionic acid, blood-brain barrier, Evans blue, Huntington's disease, StriatumAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusAntiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopus3-Nitropropionic acid activates calpain/cdk5 pathway in rat striatum
ArticleAbstract: 3-Nitropropionic acid (3-NP) is a neurotoxin that inhibits mitochondrial complex II and is used in aPalabras claves:3-nitropropionic acid, Calpain, CDK5, MEF2Autores:Antoni Camins, Canudas A.M., Crespo-Biel N., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusA new method for determining blood-brain barrier integrity based on intracardiac perfusion of an Evans Blue-Hoechst cocktail
ArticleAbstract: A new method for determining brain regions with blood-brain barrier (BBB) alterations is described.Palabras claves:blood-brain barrier, Cryoinjury, Evans blue, Fluorescence, Hoechst, Immunohistochemistry, tracersAutores:Antoni Camins, Del Valle J., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusCell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid
ArticleAbstract: This study was undertaken to investigate the potential role of cell cycle re-entry in an experimentaPalabras claves:apoptosis, cell cycle, Huntington's disease, StriatumAutores:Antoni Camins, Crespo-Biel N., Del Valle J., Duran-Vilaregut J., Ferrer I., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusCerebral amyloid angiopathy, blood-brain barrier disruption and amyloid accumulation in SAMP8 mice
ArticleAbstract: Cerebrovascular dysfunction and β-amyloid peptide deposition on the walls of cerebral blood vesselsPalabras claves:Alzheimer's disease, Amyloid accumulation, blood-brain barrier, Cerebral amyloid angiopathy, late-onset Alzheimer's disease, SAMP8 miceAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusGSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons
ArticleAbstract: In the present study, we evaluated the effects of roscovitine (Rosco) and flavopiridol (Flavo), bothPalabras claves:apoptosis, Cerebellar granular cells, flavopiridol, GSK3β, RoscovitineAutores:Antoni Camins, Auladell C., de la Torre A.V., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusExpression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase-3β in the striatum of rats treated with 3-nitropropionic acid
ArticleAbstract: 3-Nitropropionic acid (3-NPA) is a mitochondrial toxin used in the laboratory to replicate neurodegePalabras claves:Immunohistochemistry, Neurotoxin, RATAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusEarly amyloid accumulation in the hippocampus of SAMP8 mice
ArticleAbstract: Late-onset Alzheimer's disease (AD) is the most common form of AD appearing after 65 years of age. TPalabras claves:aging, Alzheimer's disease, Amyloid-β, Aβ40, Aβ42, AβPP, hippocampus, SAMP8, SAMR1, SenescenceAutores:Antoni Camins, Casadesús G., Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.Fuentes:scopus