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scopus(17)
Clustered granules present in the hippocampus of aged mice result from a degenerative process affecting astrocytes and their surrounding neuropil
ArticleAbstract: Clusters of pathological granular structures appear and progressively increase in number with age inPalabras claves:aging, Astrocyte, Granules, hippocampus, Neo-epitope, Periodic acid-Schiff, SAMP8Autores:Antoni Camins, Cabezón I., Liberski P.P., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusAn evaluation of the neuroprotective effects of melatonin in an in vitro experimental model of age-induced neuronal apoptosis
ArticleAbstract: The neuroprotective effects of melatonin in an experimental model of aging-induced apoptosis have bePalabras claves:aging, cell cycle, Neurodegeneration, P53Autores:Antoni Camins, Pallás M., Pelegrí Gabalda C., Tajes Orduña M., Vilaplana J.Fuentes:scopusA new method for determining blood-brain barrier integrity based on intracardiac perfusion of an Evans Blue-Hoechst cocktail
ArticleAbstract: A new method for determining brain regions with blood-brain barrier (BBB) alterations is described.Palabras claves:blood-brain barrier, Cryoinjury, Evans blue, Fluorescence, Hoechst, Immunohistochemistry, tracersAutores:Antoni Camins, Del Valle J., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusDietary resveratrol prevents Alzheimer's markers and increases life span in SAMP8
ArticleAbstract: Resveratrol is a polyphenol that is mainly found in grapes and red wine and has been reported to bePalabras claves:Alzheimer's disease, AMPK, Memory impairment, Resveratrol, Senescence, Sirtuin 1, Tau, β-AmyloidAutores:Antoni Camins, Bayod S., Canudas A.M., Casadesús G., Del Valle J., Pallás M., Pelegrí Gabalda C., Porquet D., Sanfeliu C., Vicente A., Vilaplana J.Fuentes:scopusCell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid
ArticleAbstract: This study was undertaken to investigate the potential role of cell cycle re-entry in an experimentaPalabras claves:apoptosis, cell cycle, Huntington's disease, StriatumAutores:Antoni Camins, Crespo-Biel N., Del Valle J., Duran-Vilaregut J., Ferrer I., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusCerebral amyloid angiopathy, blood-brain barrier disruption and amyloid accumulation in SAMP8 mice
ArticleAbstract: Cerebrovascular dysfunction and β-amyloid peptide deposition on the walls of cerebral blood vesselsPalabras claves:Alzheimer's disease, Amyloid accumulation, blood-brain barrier, Cerebral amyloid angiopathy, late-onset Alzheimer's disease, SAMP8 miceAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusGSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons
ArticleAbstract: In the present study, we evaluated the effects of roscovitine (Rosco) and flavopiridol (Flavo), bothPalabras claves:apoptosis, Cerebellar granular cells, flavopiridol, GSK3β, RoscovitineAutores:Antoni Camins, Auladell C., de la Torre A.V., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusExpression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase-3β in the striatum of rats treated with 3-nitropropionic acid
ArticleAbstract: 3-Nitropropionic acid (3-NPA) is a mitochondrial toxin used in the laboratory to replicate neurodegePalabras claves:Immunohistochemistry, Neurotoxin, RATAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusPI3 k/akt inhibition induces apoptosis through p38 activation in neurons
ArticleAbstract: Accumulating evidence suggests that the PI3 K/AKT pathway is a pro-survival signalling system in neuPalabras claves:Akt, BH3 only proteins, BIM, Dp5, LY294002, Neurons, p38 MAPKAutores:Antoni Camins, Auladell C., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Vázquez De La Torre A., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusIncreased permeability of blood-brain barrier on the hippocampus of a murine model of senescence
ArticleAbstract: SAMP8 mice show several indicative characteristics of accelerated aging and have been used to studyPalabras claves:blood-brain barrier, Confocal microscopy, hippocampus, IgG quantification, Immunohistochemistry, mouse, SAMP8, SenescenceAutores:Antoni Camins, Canudas A.M., Casadesús G., Del Valle J., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.Fuentes:scopus