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International Journal of Developmental Neuroscience(1)
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Blood-brain barrier disruption in the striatum of rats treated with 3-nitropropionic acid
ArticleAbstract: 3-Nitropropionic acid (3-NPA) is a natural toxin that is used to induce models of Huntington's diseaPalabras claves:3-nitropropionic acid, blood-brain barrier, Evans blue, Huntington's disease, StriatumAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusA new method for determining blood-brain barrier integrity based on intracardiac perfusion of an Evans Blue-Hoechst cocktail
ArticleAbstract: A new method for determining brain regions with blood-brain barrier (BBB) alterations is described.Palabras claves:blood-brain barrier, Cryoinjury, Evans blue, Fluorescence, Hoechst, Immunohistochemistry, tracersAutores:Antoni Camins, Del Valle J., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusCerebral amyloid angiopathy, blood-brain barrier disruption and amyloid accumulation in SAMP8 mice
ArticleAbstract: Cerebrovascular dysfunction and β-amyloid peptide deposition on the walls of cerebral blood vesselsPalabras claves:Alzheimer's disease, Amyloid accumulation, blood-brain barrier, Cerebral amyloid angiopathy, late-onset Alzheimer's disease, SAMP8 miceAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusIncreased permeability of blood-brain barrier on the hippocampus of a murine model of senescence
ArticleAbstract: SAMP8 mice show several indicative characteristics of accelerated aging and have been used to studyPalabras claves:blood-brain barrier, Confocal microscopy, hippocampus, IgG quantification, Immunohistochemistry, mouse, SAMP8, SenescenceAutores:Antoni Camins, Canudas A.M., Casadesús G., Del Valle J., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.Fuentes:scopusTrafficking of Gold Nanoparticles Coated with the 8D3 Anti-Transferrin Receptor Antibody at the Mouse Blood-Brain Barrier
ArticleAbstract: Receptor-mediated transcytosis has been widely studied as a possible strategy to transport neurotherPalabras claves:blood-brain barrier, drug delivery, Electron microscopy, monoclonal antibodies, receptor-mediated transport, Transferrin receptorAutores:Antoni Camins, Cabezón I., Manich G., Martín-Venegas R., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusRole of matrix metalloproteinase-9 (MMP-9) in striatal blood-brain barrier disruption in a 3-nitropropionic acid model of Huntington's disease
ArticleAbstract: Aim: 3-Nitropropionic acid (3-NPA) is a natural toxin that, when administered to experimental animalPalabras claves:3-nitropropionic acid, blood-brain barrier, Huntington's disease, Immunohistochemistry, Matrix metallopro teinase, StriatumAutores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusStudy of the transcytosis of an anti-transferrin receptor antibody with a Fab′ cargo across the blood-brain barrier in mice
ArticleAbstract: One strategy used to transport pharmacologically active substances across the blood-brain barrier (BPalabras claves:8D3 antibody, blood-brain barrier, receptor-mediated transcytosis, Transferrin receptorAutores:Antoni Camins, Cabezón I., Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopusTime-course of blood-brain barrier disruption in senescence-accelerated mouse prone 8 (SAMP8) mice
ArticleAbstract: Senescence of the cerebrovascular system and an abnormal function of the blood-brain barrier have bePalabras claves:Alzheimer's disease, blood-brain barrier, Evans blue, SAMP8, SAMR1Autores:Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.Fuentes:scopus