Documentos de Pelegrí Gabalda C. | REDI

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Mostrando 10 resultados de: 22

Filtros aplicados

Objetivos de Desarrollo Sostenible: "ODS 10: Reducción de las desigualdades"

Subtipo de publicación

Publisher

Journal of Alzheimer's Disease(2)

Neurochemistry International(2)

Pharmacological Research(2)

Biochimica et Biophysica Acta - Gene Regulatory Mechanisms(1)

Área temáticas

Enfermedades(18)

Fisiología humana(12)

Farmacología y terapéutica(7)

Fisiología y materias afines(4)

Área de conocimiento

Neurología(15)

Neuropsicología(8)

Biología celular(6)

Biología molecular(1)

Objetivos de Desarrollo Sostenible

ODS 3: Salud y bienestar(22)

ODS 9: Industria, innovación e infraestructura(13)

ODS 12: Producción y consumo responsables(5)

ODS 17: Alianzas para lograr los objetivos(3)

ODS 2: Hambre cero(1)

Año de Publicación

Origen

Palabras Claves

blood-brain barrier(7)

Alzheimer's disease(4)

3-Nitropropionic acid activates calpain/cdk5 pathway in rat striatum

Abstract: 3-Nitropropionic acid (3-NP) is a neurotoxin that inhibits mitochondrial complex II and is used in a

Palabras claves:

3-nitropropionic acid, Calpain, CDK5, MEF2

Antoni Camins, Canudas A.M., Crespo-Biel N., Pallás M., Pelegrí Gabalda C., Vilaplana J.

A new method for determining blood-brain barrier integrity based on intracardiac perfusion of an Evans Blue-Hoechst cocktail

Abstract: A new method for determining brain regions with blood-brain barrier (BBB) alterations is described.

Palabras claves:

blood-brain barrier, Cryoinjury, Evans blue, Fluorescence, Hoechst, Immunohistochemistry, tracers

Antoni Camins, Del Valle J., Pallás M., Pelegrí Gabalda C., Vilaplana J.

Clustered granules present in the hippocampus of aged mice result from a degenerative process affecting astrocytes and their surrounding neuropil

Abstract: Clusters of pathological granular structures appear and progressively increase in number with age in

Palabras claves:

aging, Astrocyte, Granules, hippocampus, Neo-epitope, Periodic acid-Schiff, SAMP8

Antoni Camins, Cabezón I., Liberski P.P., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.

Blood-brain barrier disruption in the striatum of rats treated with 3-nitropropionic acid

Abstract: 3-Nitropropionic acid (3-NPA) is a natural toxin that is used to induce models of Huntington's disea

Palabras claves:

3-nitropropionic acid, blood-brain barrier, Evans blue, Huntington's disease, Striatum

Antoni Camins, Del Valle J., Duran-Vilaregut J., Pallás M., Pelegrí Gabalda C., Vilaplana J.

An evaluation of the neuroprotective effects of melatonin in an in vitro experimental model of age-induced neuronal apoptosis

Abstract: The neuroprotective effects of melatonin in an experimental model of aging-induced apoptosis have be

Palabras claves:

aging, cell cycle, Neurodegeneration, P53

Antoni Camins, Pallás M., Pelegrí Gabalda C., Tajes Orduña M., Vilaplana J.

Antiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases

Abstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodeg

Palabras claves:

Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's Disease

Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.

Early amyloid accumulation in the hippocampus of SAMP8 mice

Abstract: Late-onset Alzheimer's disease (AD) is the most common form of AD appearing after 65 years of age. T

Palabras claves:

aging, Alzheimer's disease, Amyloid-β, Aβ40, Aβ42, AβPP, hippocampus, SAMP8, SAMR1, Senescence

Antoni Camins, Casadesús G., Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.

GSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons

Abstract: In the present study, we evaluated the effects of roscovitine (Rosco) and flavopiridol (Flavo), both

Palabras claves:

apoptosis, Cerebellar granular cells, flavopiridol, GSK3β, Roscovitine

Antoni Camins, Auladell C., de la Torre A.V., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Verdaguer E., Vilaplana J., Zárate C.B.

Increased permeability of blood-brain barrier on the hippocampus of a murine model of senescence

Abstract: SAMP8 mice show several indicative characteristics of accelerated aging and have been used to study

Palabras claves:

blood-brain barrier, Confocal microscopy, hippocampus, IgG quantification, Immunohistochemistry, mouse, SAMP8, Senescence

Antoni Camins, Canudas A.M., Casadesús G., Del Valle J., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.

Study of the pathways involved in apoptosis induced by PI3K inhibition in cerebellar granule neurons

Abstract: In the present study we focused in the PI3K/Akt pathway which plays a key role in neuronal survival.

Palabras claves:

BrdU, Caspase-6, Cdk5/p25, cell cycle, LY294002

Antoni Camins, Auladell C., Folch J., Junyent F., Palls M., Pelegrí Gabalda C., Torre A.V.D.L., Verdaguer E., Vilaplana J., Zárate C.B.