Documentos de Pelegrí Gabalda C.

Regresar

Mostrando 10 resultados de: 15

3-Nitropropionic acid activates calpain/cdk5 pathway in rat striatum

Article

Abstract: 3-Nitropropionic acid (3-NP) is a neurotoxin that inhibits mitochondrial complex II and is used in a

Palabras claves:

3-nitropropionic acid, Calpain, CDK5, MEF2

Autores:

Antoni Camins, Canudas A.M., Crespo-Biel N., Pallás M., Pelegrí Gabalda C., Vilaplana J.

Fuentes:

scopus

A new method for determining blood-brain barrier integrity based on intracardiac perfusion of an Evans Blue-Hoechst cocktail

Article

Abstract: A new method for determining brain regions with blood-brain barrier (BBB) alterations is described.

Palabras claves:

blood-brain barrier, Cryoinjury, Evans blue, Fluorescence, Hoechst, Immunohistochemistry, tracers

Autores:

Antoni Camins, Del Valle J., Pallás M., Pelegrí Gabalda C., Vilaplana J.

Fuentes:

scopus

Antiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases

Review

Abstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodeg

Palabras claves:

Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's Disease

Autores:

Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.

Fuentes:

scopus

Early amyloid accumulation in the hippocampus of SAMP8 mice

Article

Abstract: Late-onset Alzheimer's disease (AD) is the most common form of AD appearing after 65 years of age. T

Palabras claves:

aging, Alzheimer's disease, Amyloid-β, Aβ40, Aβ42, AβPP, hippocampus, SAMP8, SAMR1, Senescence

Autores:

Antoni Camins, Casadesús G., Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Smith M.A., Vilaplana J.

Fuentes:

scopus

GSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons

Article

Abstract: In the present study, we evaluated the effects of roscovitine (Rosco) and flavopiridol (Flavo), both

Palabras claves:

apoptosis, Cerebellar granular cells, flavopiridol, GSK3β, Roscovitine

Autores:

Antoni Camins, Auladell C., de la Torre A.V., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Verdaguer E., Vilaplana J., Zárate C.B.

Fuentes:

scopus

Expression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase-3β in the striatum of rats treated with 3-nitropropionic acid

Article

Abstract: 3-Nitropropionic acid (3-NPA) is a mitochondrial toxin used in the laboratory to replicate neurodege

Palabras claves:

Immunohistochemistry, Neurotoxin, RAT

Autores:

Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.

Fuentes:

scopus

Study of the pathways involved in apoptosis induced by PI3K inhibition in cerebellar granule neurons

Article

Abstract: In the present study we focused in the PI3K/Akt pathway which plays a key role in neuronal survival.

Palabras claves:

BrdU, Caspase-6, Cdk5/p25, cell cycle, LY294002

Autores:

Antoni Camins, Auladell C., Folch J., Junyent F., Palls M., Pelegrí Gabalda C., Torre A.V.D.L., Verdaguer E., Vilaplana J., Zárate C.B.

Fuentes:

scopus

Study of the transcytosis of an anti-transferrin receptor antibody with a Fab′ cargo across the blood-brain barrier in mice

Article

Abstract: One strategy used to transport pharmacologically active substances across the blood-brain barrier (B

Palabras claves:

8D3 antibody, blood-brain barrier, receptor-mediated transcytosis, Transferrin receptor

Autores:

Antoni Camins, Cabezón I., Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.

Fuentes:

scopus

Time-course of blood-brain barrier disruption in senescence-accelerated mouse prone 8 (SAMP8) mice

Article

Abstract: Senescence of the cerebrovascular system and an abnormal function of the blood-brain barrier have be

Palabras claves:

Alzheimer's disease, blood-brain barrier, Evans blue, SAMP8, SAMR1

Autores:

Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.

Fuentes:

scopus

Neuronal apoptosis in the striatum of rats treated with 3-nitropropionic acid is not triggered by cell-cycle re-entry

Article

Abstract: Although terminally differentiated neurons lack the capacity to undergo cell division, they retain t

Palabras claves:

3-nitropropionic acid, apoptosis, Cell-cycle re-entry, Immunohistochemistry, Neurodegeneration

Autores:

Antoni Camins, Del Valle J., Duran-Vilaregut J., Manich G., Pallás M., Pelegrí Gabalda C., Vilaplana J.

Fuentes:

scopus

Mostrando 10 resultados de: 15

Filtros aplicados

Subtipo de publicación

Publisher

Área temáticas

Área de conocimiento

Objetivos de Desarrollo Sostenible

Año de Publicación

Origen

Palabras Claves

3-Nitropropionic acid activates calpain/cdk5 pathway in rat striatum

A new method for determining blood-brain barrier integrity based on intracardiac perfusion of an Evans Blue-Hoechst cocktail

Antiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases

Early amyloid accumulation in the hippocampus of SAMP8 mice

GSK3β inhibition is involved in the neuroprotective effects of cyclin-dependent kinase inhibitors in neurons

Expression pattern of ataxia telangiectasia mutated (ATM), p53, Akt, and glycogen synthase kinase-3β in the striatum of rats treated with 3-nitropropionic acid

Study of the pathways involved in apoptosis induced by PI3K inhibition in cerebellar granule neurons

Study of the transcytosis of an anti-transferrin receptor antibody with a Fab′ cargo across the blood-brain barrier in mice

Time-course of blood-brain barrier disruption in senescence-accelerated mouse prone 8 (SAMP8) mice

Neuronal apoptosis in the striatum of rats treated with 3-nitropropionic acid is not triggered by cell-cycle re-entry