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Comparison of the Opn-CreER and Ck19-CreER drivers in bile ducts of normal and injured mouse livers
OtherAbstract: Inducible cyclization recombinase (Cre) transgenic mouse strains are powerful tools for cell lineagePalabras claves:Bile duct cells, Cholangiocytes, Ck19, Cre, Knockout, Lineage tracing, Mouse liver, OpnAutores:Grunsven L., Halder G., Huffel L., Ivánm Moya, Leclercq I., Lemaigre F.P., Lesaffer B., Verboven E.Fuentes:scopusFunctionality based method for simultaneous isolation of rodent hepatic sinusoidal cells
ArticleAbstract: Chronic liver disease is the result of long term exposure to viruses or toxins such as alcohol, fatPalabras claves:FACS, Hepatic stellate cells, IGG, Kupffer cells, Liver sinusoidal endothelial cells, ScavengingAutores:Halder G., Iván M. Moya, Mannaerts I., Roosens T., Stradiot L., van Grunsven L.A., Verhulst S., Øie C.I.Fuentes:googlescopusDifferential regulation of the Hippo pathway by adherens junctions and apical- Basal cell polarity modules
ArticleAbstract: Adherens junctions (AJs) and cell polarity complexes are key players in the establishment and maintePalabras claves:Autores:Gladden A.B., Graves H.K., Halder G., Hamaratoglu F., Iván M. Moya, Tao C., Yang C.C.Fuentes:googlescopusDiscovering the Hippo pathway protein-protein interactome
ArticleAbstract:Palabras claves:Autores:Halder G., Iván M. MoyaFuentes:googlescopusHippo signaling instructs ectopic but not normal organ growth
ArticleAbstract: The Hippo signaling pathway is widely considered a master regulator of organ growth because of the pPalabras claves:Autores:Aerts S., Atkins M., de Waegeneer M., González-Blas C.B., Halder G., Hillen H., Iván M. Moya, Jacobs J., Johnson R.L., Kowalczyk W., Romanelli L., Sansores-Garcia L., Soheily S., van Grunsven L.A., Van Huffel L., Verboven E., Verhulst S., Xie J.Fuentes:googlescopusHippo–YAP/TAZ signalling in organ regeneration and regenerative medicine
ReviewAbstract: The Hippo pathway and its downstream effectors, the transcriptional co-activators Yes-associated proPalabras claves:Autores:Halder G., Iván M. MoyaFuentes:googlescopusMask is required for the activity of the hippo pathway effector Yki/YAP
ArticleAbstract: The Drosophila Yorkie (Yki) protein and its mammalian homolog Yes-associated protein (YAP) are potenPalabras claves:Autores:Atkins M., Halder G., Iván M. Moya, Mills G.B., Sansores-Garcia L., Shahmoradgoli M., Tao C.Fuentes:googlescopusPeritumoral activation of the Hippo pathway effectors YAP and TAZ suppresses liver cancer in mice
ArticleAbstract: The Hippo signaling pathway and its two downstream effectors, the YAP and TAZ transcriptional coactiPalabras claves:Autores:Aerts S., Algueró-Nadal A., Castaldo S.A., de Waegeneer M., Halder G., Hillen H., Iván M. Moya, Jacobs J., Johnson R.L., Karaman R., Karras P., Kowalczyk W., Mannaerts I., Marine J.C., Roskams T., Sansores-Garcia L., Soheily S., Van den Mooter L., van Grunsven L.A., van Haele M., Van Huffel L., Verboven E., Verhulst S., Xie J., Zender L.Fuentes:googlescopusYAP and TAZ heterogeneity in primary liver cancer: An analysis of its prognostic and diagnostic role
ArticleAbstract: Primary liver cancer comprises a diverse group of liver tumors. The heterogeneity of these tumors isPalabras claves:CCA, CHCC-CCA, HCC, Hepatic progenitor cells, Keratin 19, TAZ, YAPAutores:Govaere O., Halder G., Iván M. Moya, Karaman R., Monbaliu D., Nevens F., Rens G., Roskams T., Snoeck J., Topal B., van Haele M., Verslype C.Fuentes:googlescopusYAP/TAZ Orchestrate VEGF Signaling during Developmental Angiogenesis
ArticleAbstract: Vascular endothelial growth factor (VEGF) is a major driver of blood vessel formation. However, thePalabras claves:Angiogenesis, CNS vascularization, endothelial cells, hippo pathway, TAZ, VEGF, VEGFR2, YAP, YAP/TAZAutores:Castro L., Fischer T., Freire Valls A., Halder G., Iván M. Moya, Jain R.K., Mazzone M., Riedemann L., Ruiz de Almodóvar C., Schermann G., Schmidt T., Shen Y., Solecki G.M., Urban S., Wang X., Winkler F.Fuentes:googlescopus