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Clinical Implications of Epigenetic Dysregulation in Perinatal Hypoxic-Ischemic Brain Damage
ReviewAbstract: Placental and fetal hypoxia caused by perinatal hypoxic-ischemic events are major causes of stillbirPalabras claves:Biomarker, DNA methylation, histone modifications, Hypoxia, hypoxic-ischemic encephalopathy, ischemia, microRNAsAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Bruno M.A., Bustelo M., Loidl C.F., Steinbusch H.W.M., van den Hove D.L.A.Fuentes:scopusAntenatal and Perioperative Mechanisms of Global Neurological Injury in Congenital Heart Disease
ReviewAbstract: Congenital heart defects (CHD) is one of the most common types of birth defects. Thanks to advancesPalabras claves:Brain injury, congenital heart disease, Hypoplastic left heart syndrome, Immaturity, SurgeryAutores:Abella R., Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Gazzolo D., Vles J.S.H., Zimmermann L.J.I.Fuentes:scopus25 years of research on global asphyxia in the immature rat brain
ReviewAbstract: Hypoxic-ischemic encephalopathy remains a common cause of brain damage in neonates. Preterm infantsPalabras claves:Encephalopathy, functional outcome, Hypoxic-ischemia, Preterm infant, SubmersionAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Kramer B.W., Steinbusch H.W.M., van den Hove D.L.A., Vles J.S.H.Fuentes:scopusNitric Oxide Production in the Striatum and Cerebellum of a Rat Model of Preterm Global Perinatal Asphyxia
ArticleAbstract: Encephalopathy due to perinatal asphyxia (PA) is a major cause of neonatal morbidity and mortality iPalabras claves:asphyxia, cGMP, Neuronal nitric oxide synthase, Nitrosidative stress, Peroxynitrite, Selective vulnerabilityAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Blanco C.E., De Vente J., Steinbusch H.W.M., Van de Berg W.D.J.Fuentes:scopusPerinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis
ArticleAbstract: Introduction: The age of diagnosis of Huntington's disease (HD) varies among individuals with the saPalabras claves:Developmental disorders, Epidemiological, Huntington's disease, Modifier, neonatalAutores:Anderson D.G., Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Kramer B.W., Rodrigues F.B., Wild E.J., Winkens B.Fuentes:scopusUsing global team science to identify genetic parkinson's disease worldwide
OtherAbstract:Palabras claves:Autores:Aasly J., Adler C., Ahmad-Annuar A., Al-Mubarak B., Albanese A., Alcalay R.N., Alvarez V., Andree-Muñoz B., Annesi G., Appel-Cresswell S., Arkadir D., Armasu S., Barber T.R., Bardien S., Barkhuizen M., Barrett M.J., Başak A.N., Beach T., Belin A.C., Benitez B.A., Berg D., Bhatia K., Binkofski F., Blauwendraat C., Bonifati V., Borges V., Bozi M., Brice A., Brighina L., Brockmann K., Brücke T., Brüggemann N., Camacho M., Cardoso F., Carr J., Chan P., Chase B., Chen-Plotkin A., Cilia R., Clarimon J., Clark L., Cornejo-Olivas M., Corvol J.C., Cosentino C., Cras P., Crosiers D., Damásio J., Das P., de Carvalho Aguiar P., De Michele G., De Rosa A., Dieguez E., Dorszewska J., Erer S., Ertan S., Farrer M., Fedotova E., Ferese R., Ferrarese C., Ferraz H.B., Fiala O., Foroud T., Friedman A., Frigerio R., Funayama M., Gambardella S., Garraux G., Gatto E.M., Genç G., Giladi N., Goldwurm S., Gomez-Esteban J.C., Gómez-Garre P., Gorostidi A., Grosset D., Hanagasi H., Hardy J., Hassan A., Hattori N., Hauser R.A., Hedera P., Hentati F., Hertz J.M., Holton J.L., Houlden H., Hutz M.H., Ikeuchi T., Illarioshkin S., Inca-Martinez M., Infante J., Jankovic J., Jeon B.S., Jesús S., Jimenez-Del-Rio M., Jorge Chang-Castello, Ju Chung S., Kaasinen V., Kasten M., Klein C., Vollstedt E.J.Fuentes:scopusPreterm perinatal hypoxia-ischemia does not affect somatosensory evoked potentials in adult rats
ArticleAbstract: Somatosensory evoked potentials (SSEPs) are a valuable tool to assess functional integrity of the soPalabras claves:Cerebral palsy, Hypoxia-ischemia, Preterm brain, Rat model, Somatosensory evoked potentialAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Bergs P., Kramer B.W., Peter A. Chedraui, van Kranen-Mastenbroek V.H.J.M., van Mechelen R., Vermeer M., Vles J.S.H.Fuentes:scopusSystemic multipotent adult progenitor cells improve long-term neurodevelopmental outcomes after preterm hypoxic-ischemic encephalopathy
ArticleAbstract: There is an urgent need for therapies that could reduce the disease burden of preterm hypoxic-ischemPalabras claves:hypoxic-ischemic encephalopathy, Neurodevelopment, Preterm brain, Stem cell therapyAutores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Kramer B.W., Mays R.W., Paes D., Peter A. Chedraui, Robertson N.J., Steinbusch H.W.M., Vaes B., van den Hove D.L.A., van Mechelen R., Vermeer M.Fuentes:scopusThe influence of anesthetics on substantia nigra tyrosine hydroxylase expression and tau phosphorylation in the hypoxic-ischemic near-term lamb
ArticleAbstract: BackgroundGeneral anesthetics could protect key neurotransmitter systems, such as the dopaminergic sPalabras claves:Autores:Antonio Wenceslao Danilo Gavilanes, Barkhuizen M., Cleutjens J.P.M., Engelbertink I., Gussenhoven R., Jellema R.K., Kramer B.W., Seehase M., Steinbusch H.W.M., Van Dijck F.J.P., van Mechelen R., Zimmermann L.J.I.Fuentes:scopus