Mostrando 8 resultados de: 8
Subtipo de publicación
Article(8)
Publisher
Antiviral Chemistry and Chemotherapy(2)
Advances in Experimental Medicine and Biology(1)
Antiviral Research(1)
Bioorganic and Medicinal Chemistry(1)
Bioorganic and Medicinal Chemistry Letters(1)
Área temáticas
Farmacología y terapéutica(7)
Enfermedades(4)
Bioquímica(3)
Cristalografía(1)
Fisiología humana(1)
Área de conocimiento
Farmacología(7)
Bioquímica(2)
Ciencias de la computación(1)
Descubrimiento de fármacos(1)
Infección(1)
Objetivos de Desarrollo Sostenible
ODS 3: Salud y bienestar(8)
ODS 10: Reducción de las desigualdades(7)
ODS 5: Igualdad de género(4)
ODS 9: Industria, innovación e infraestructura(3)
ODS 12: Producción y consumo responsables(1)
Origen
scopus(8)
Characterization of the activation pathway of phosphoramidate triester prodrugs of stavudine and zidovudine
ArticleAbstract: The phosphoramidate triester prodrugs of anti-human HIV 2',3'- dideoxynucleoside analogs (ddN) reprePalabras claves:Autores:Antonio Salgado, Balzarini J., Cahard D., De Clercq E., McGuigan C., Naesens L., Pathirana R., Saboulard D., Velázquez S.Fuentes:scopusQSAR for anti-RNA-virus activity, synthesis, and assay of anti-RSV carbonucleosides given a unified representation of spectral moments, quadratic, and topologic indices
ArticleAbstract: The unified representation of spectral moments, classic topologic indices, quadratic indices, and stPalabras claves:Antiviral activity, Carbonucleosides synthesis, Markov models, QSAR, Quadratic Indices, Spectral moments, Topologic indicesAutores:De Clercq E., González‐díaz H., Maykel Cruz-Monteagudo, Santana L., Uriarte E., Viña D.Fuentes:scopusMarked inhibitory activity of masked aryloxy aminoacyl phosphoramidate derivatives of dideoxynucleoside analogues against visna virus infection
ArticleAbstract: Lipophilic masked aryloxyaminoacylphosphoramidate derivatives of 2',3'- dideoxynucleoside (ddN) analPalabras claves:(Dideoxy)nucleoside analogues, AIDs, hiv, Masked aryloxyaminoacylphosphoramidate (dideoxy)nucleoside analogues, Reverse transcriptase, Visna virusAutores:Antonio Salgado, Balzarini J., Cahard D., De Clercq E., McGuigan C., Thormar H., Velázquez S., Wedgwood O., Yarnold C.J.Fuentes:scopusMetabolism and anti-HIV activity of phosphoramidate derivatives of D4T-MP with variations in the amino acid moiety
ArticleAbstract: The metabolism of different phosphoramidate prodrugs of d4T-MP, in which the phosphate group is linkPalabras claves:Autores:Antonio Salgado, Baizarini J., Bidois L., Cahard D., De Clercq E., McGuigan C., Naesens L.Fuentes:scopusPhosphoramidate derivatives of d4T as inhibitors of HIV: The effect of amino acid variation
ArticleAbstract: Phosphoramidate derivatives of the nucleoside analogue, 2',3'-dideoxy-2',3'-didehydro thymidine (d4TPalabras claves:2',3'-Dideoxy-2',3'-didehydro thymidine, hiv, Nucleotide, Phosphoramidate, Pro-drugAutores:Antonio Salgado, Balzarini J., Bidois L., Cahard D., De Clercq E., McGuigan C., Naesens L., Tsang H.W., Turner K., Velázquez S.Fuentes:scopusPhosphoramidates as potent prodrugs of anti-HIV nucleotides: Studies in the amino region
ArticleAbstract: Novel phosphoramidate derivatives of the anti-HIV nucleoside analogues AZT and d4T have been preparePalabras claves:AZT, d4T, hiv, Nucleotide, ProdrugAutores:Antonio Salgado, Baizarinl J., Cahard D., De Clercq E., McGuigan C.Fuentes:scopusNovel nucleoside phosphoramidates as inhibitors of HIV: Studies on the stereochemical requirements of the phosphoramidate amino acid
ArticleAbstract: Novel phosphoramidate derivatives of the anti-HIV nucleoside analogue d4T were designed to act as laPalabras claves:d4T, hiv, Nucleotide, Phosphoramidate, Prodrug, Reverse transcriptaseAutores:Antonio Salgado, Balzarini J., De Clercq E., Harries T.Y., McGuigan C., Yarnold C.J.Fuentes:scopusSynthesis and pharmacological evaluation of several ring-contracted amantadine analogs
ArticleAbstract: The synthesis of several (3-noradamantyl)amines, [(3-noradamantyl)methyl]amines, (3,7-dimethyl-1-bisPalabras claves:Amantadine, influenza, Memantine, NMDA receptor antagonist, Polycyclic cage compounds, TrypanosomiasisAutores:Antoni Camins, Camps P., Cortés D., De Clercq E., Duque M.D., Ivorra D., Kelly J.M., López-Querol M., Naesens L., Pallás M., Prathalingam S.R., Romero V., Sureda F.X., Vázquez S.Fuentes:scopus