Mostrando 3 resultados de: 3
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Article(3)
Publisher
Cell(1)
Clinical Cancer Research(1)
Proceedings of the National Academy of Sciences of the United States of America(1)
Origen
scopus(3)
Abiraterone inhibits 3β-hydroxysteroid dehydrogenase: A rationale for increasing drug exposure in castration-resistant prostate cancer
ArticleAbstract: Purpose: Treatment with abiraterone (abi) acetate prolongs survival in castration-resistant prostatePalabras claves:Autores:Chang K.H., Evaul K., Li R., Liu J., Richard J. Auchus, Sharifi N., Sharma K.K., Yoshimoto J.A.Fuentes:scopusDihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
ArticleAbstract: In the majority of cases, advanced prostate cancer responds initially to androgen deprivation therapPalabras claves:5-alpha-androstanedione, Abiraterone acetate, Hormonal therapy, Hormone resistance, Tumor metabolismAutores:Chang K.H., Li R., Papari-Zareei M., Richard J. Auchus, Sharifi N., Watumull L., Zhao Y.Fuentes:scopusXA gain-of-function mutation in DHT synthesis in castration-resistant prostate cancer
ArticleAbstract: Growth of prostate cancer cells is dependent upon androgen stimulation of the androgen receptor (AR)Palabras claves:Autores:Chang K.H., Guo X., Kapur P., Kuri B., Li R., Liu J., Lotan Y., Mirzaei H., Nelson P.S., Richard J. Auchus, Roehrborn C.G., Sharifi N., Vessella R.Fuentes:scopus