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Article(6)
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Cell Reports Medicine(1)
Immunity(1)
Journal of Allergy and Clinical Immunology(1)
Nature Medicine(1)
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scopus(6)
Characterization of the clinical and immunologic phenotype and management of 157 individuals with 56 distinct heterozygous NFKB1 mutations
ArticleAbstract: Background: An increasing number of NFKB1 variants are being identified in patients with heterogeneoPalabras claves:Autosomal dominant, common variable immunodeficiency, NF-κB1-related phenotype, NFKB1 mutation, NFKB1 variant, reduced penetranceAutores:Abolhassani H., Adhya Z., Aghamohammadi A., Alachkar H., Allen H.L., Allende L.M., Alosaimi M., Alsina L., Ameratunga R., Anantharachagan A., Antrobus R., Arumugakani G., Ashford S., Astle W.J., Atschekzei F., Attwood A., Bacchelli C., Bakhtiar S., Barış S., Bartsch O., Batista J., Baxendale H.E., Bethune C., Bibi S., Bleda M., Boardman B., Booth C., Boztug K., Bradley J.R., Brauer N., Breen G., Brown M., Browning M.J., Brownlie M., Buckland M.S., Bulashevska A., Burns S.O., Burren O.S., Camacho-Ordonez N., Carss K., Chambers J., Chandra A., Chou J., Christiansen M., Cook M., Cunningham-Rundles C., de Vries E., Deyà-Martínez A., Dos Santos Vilela M.M., Fischer U., Fliegauf M., Frede N., Freeman A.F., Geha R., Gonzalez-Granado L.I., Grimbacher B., Hammarström L., Hautala T., Helminen M., Hirschmugl T., Holzinger D., Ip W., Kinnunen M., Klammer N., Klein C., Kobbe R., Kuijpers T.W., Kuismin O., Kuzmenko N., Lorenzini T., Lougaris V., Luis Alberto Pedroza, Martínez-Gallo M., Neves J.F., Niehues T., Patel N.C., Piquer-Gibert M., Plebani A., Proietti M., Rae W., Roifman C.M., Schejter Y.D., Schmidt R.E., Schröder C., Seidl M., Seppänen M.R.J., Shadur B., Shcherbina A., Slade C.A., Stepensky P., Svec P., Syrjänen J., Thaventhiran J.E.D., Tuijnenburg P., van der Flier M., van der Meer J.W.M., Varjosalo M., Warnatz K., Weintraub L., Zakharova V.Fuentes:scopusCombined Point-of-Care Nucleic Acid and Antibody Testing for SARS-CoV-2 following Emergence of D614G Spike Variant
ArticleAbstract: Rapid COVID-19 diagnosis in the hospital is essential, although this is complicated by 30%–50% of noPalabras claves:covid-19, D614G, point of care testing, rapid diagnoses, SARS-COV-2Autores:Abeseabe R., Allain J.P., Amoroso G., Assennato S.M., Baker S., Barmpounakis P., Bates A., Bergamaschi L., Bermperi A., Blake E., Bousfield R., Boyle A., Bradley J.R., Briggs J.A.G., Brown N., Bucke A., Bundi P., Calder J., Canna L., Chapman D., Chatterjee K., Chiu E., Ciazynska K.A., Clark S., Collier D.A., Crucusio C., Curran M.D., Davidson F., de Jesus R., Demeris N., Domingo J., Dougan G., Elmer A., Emma Jones, Enoch D., Fabiculana M., Foster E., Frost S., Gkrania-Klotsas E., Goel N., Goodfellow I.G., Gupta R.K., Hardwick S., Hardy R., Harris J., Hewitt S., Hosmillo M., James L.C., Jose S., Kennet J., Kiss L., Knock H., Kourampa E., Kourampa J., Lehner P.J., Lyons P.A., Matheson N.J., Meadows A., Mendoza V., Meng B., Mescia F., Mlcochova P., Mynott L., Nathan J.A., O'Brien C., Overhill A., Palmar S., Pasquale C., Perales M., Phillips D., Price J., Ramenatte N., Rastall R., Ribeiro C., Ritchie A., Rowlands J., Rundell V., Saunders C., Shaw A., Sipple J., Skells R., Smith K.G.C., Sparkes D., Temperton N.J., Tordesillas H., Toshner M., Vallier A.L., Vargas P., Vergese B., Vicente I., Watson L., Weekes M.P., Williams A., Wilson M., Worsley J., Xiong X., Zerrudo J.A., Zhang H.Fuentes:scopusBrain injury in COVID-19 is associated with dysregulated innate and adaptive immune responses
ArticleAbstract: COVID-19 is associated with neurological complications including stroke, delirium and encephalitis.Palabras claves:Autoantibodies, Brain injury, covid-19, neuroinflammationAutores:Allinson K., Allison J., Alvio G., Ansaripour A., Anwar F., Ashton N.J., Baker S., Barcenas-Morales G., Bergamaschi L., Bermperi A., Betancourt A., Bhatti J., Biggs H., Bong S.H., Bower G., Bradley J.R., Breen G., Brookes K., Bucke A., Bullman B., Bullmore E.T., Bunclark K., Burnstein R.M., Butcher H., Caddy S., Calder J., Caller L., Canna L., Caputo D., Cavanagh J., Chandler M., Chatfield D.A., Chaudhry Y., Chinnery P.F., Christmas D., Clapham-Riley D., Coles A.J., Coles J.P., Cooper D., Correia M., Cossetti C., Crucusio C., Das T., Digby R.J., Doffinger R., Dunai C., Dunning J., Ebrahimi S., Edé A., Elmer A., Emma Jones, Fletcher P.C., Fonseca C., Gisslé M., Griffiths M.J., Irani S.R., Jubb A.W., Kingston N., Leibowitz M.M., Lupson V.C., Lyons P.A., Manktelow A.E., Marklund E., Menon D.K., Michael B.D., Michell A., Needham E.J., Newcombe V.F.J., Norton E.J., Openshaw P.J.M., Outtrim J.G., Pointon L., Ren A.L., Rodgers C.T., Rowe J.B., Rua C., Samanta R.J., Sithole N., Smith K.G.C., Spindler L.R.B., Stamatakis E.A., Summers C., Taams L.S., Taussig M.J., Taylor J., Valerio F., Widmer B., Williams G.B., Zetterberg H.Fuentes:scopusA thermostable, closed SARS-CoV-2 spike protein trimer
ArticleAbstract: The spike (S) protein of SARS-CoV-2 mediates receptor binding and cell entry and is the dominant tarPalabras claves:Autores:Baker S., Baxendale H.E., Bergamaschi L., Betancourt A., Bower G., Bradley J.R., Briggs J.A.G., Bucke A., Bullman B., Butcher H., Calder J., Canna L., Caputo D., Carter A.P., Ciazynska K.A., Crucusio C., de Sa A., Dewhust E., Doffinger R., Domingo J., Dunmore B.J., Ebrahimi S., Elmer A., Emma Jones, Epping M., Fawke S., Goodfellow I.G., Graf S., Graves B., Grice G.L., Harris J., Hewitt S., Hodgson J., Hosmillo M., Huang C., Huhn O., Hunter K., James L.C., Jarvis I., Jose S., Ke Z., Kennet J., Kourampa J., Le Gresley E., Legchenko E., Li E., Lyons P.A., Marsden J., Martin J., Meadows A., Mescia F., Nathan J.A., Nice F., Omarjee O., Ovington N., O’Brien C., O’Donnell C., Papadia S., Perera M., Pointon L., Pond N., Price J., Qu K., Rastall R., Ribeiro C., Richoz N., Rowlands J., Ruffolo V., Scheres S.H.W., Sharma R., Shih J., Smith K.G.C., Stark H., Stirrups K., Sutcliffe R., Tilly T., Tong Z., Tordesillas H., Toshner M., Treacy C., Turner L., Walker N., Wood J., Wylot M., Xiong X., Zhang Y.Fuentes:scopusLongitudinal analysis reveals that delayed bystander CD8+ T cell activation and early immune pathology distinguish severe COVID-19 from mild disease
ArticleAbstract: The kinetics of the immune changes in COVID-19 across severity groups have not been rigorously assesPalabras claves:bystander CD8+ T cell, complement, covid-19, immune pathology, INTERFERÓN, recovery, SARS-COV-2, Systemic inflammation, TNF-αAutores:Allison J., Ansaripour A., Baker S., Bergamaschi L., Betancourt A., Bong S.H., Bower G., Bradley J.R., Bucke A., Bullman B., Bunclark K., Butcher H., Calder J., Calero-Nieto F.J., Canna L., Caputo D., Clapham-Riley D., Cossetti C., Coudert J.D., de Bie E.M.D.D., de Sa A., Dewhurst E., di Stefano G., Doffinger R., Domingo J., Dougan G., Dunmore B.J., Elmer A., Emma Jones, Epping M., Fahey C., Fawke S., Fuller S., Furlong A., Gerber P.P., Gleadall N., Goodfellow I.G., Göttgens B., Graf S., Graves B., Gray J., Grenfell R., Gupta R.K., Hanson A.L., Harris J., Hess C., Hewitt S., Hinch A., Hodgson J., Holmes E., Hosmillo M., Huang C., Huhn O., Hunter K., Ivers T., Jackson S., Jarvis I., Jose S., Josipovic M., Kasanicki M., Kennet J., Kingston N., Kotagiri P., Kourampa J., Laurenti E., Le Gresley E., Legchenko E., Lehner P.J., Lewis D., Linger R., Lyons P.A., Mackay M., Marioni J.C., Marsden J., Martin J., Matara C., Matheson N.J., Meadows A., Meloy S., Mende N., Mescia F., Michael A., Michel R., Morgan M.D., Muldoon F., Mwaura L., Nice F., Nicholson J.K., Petrunkina A.M., Richardson S., Ruffieux H., Saunders C., Smith K.G.C., Thaventhiran J.E.D., Toonen E.J.M., Toshner M., Turner L., Weekes M.P., Wills M.R.Fuentes:scopusSingle-cell multi-omics analysis of the immune response in COVID-19
ArticleAbstract: Analysis of human blood immune cells provides insights into the coordinated response to viral infectPalabras claves:Autores:Bacardit J., Bach K., Baker K.F., Baker S., Barnes J.L., Barr A.S., Bergamaschi L., Botting R.A., Bradley J.R., Bucke A., Bullman B., Calder J., Calero-Nieto F.J., Canna L., Coupland P., Coxhead J.M., Dann E., de Wilton A., Domingo J., Dougan G., Dunmore B.J., Elmer A., Emma Jones, Engelbert J., Fawke S., Fuller S., Gardner L.C.S., Goh I., Goodfellow I.G., Gopee N., Gothe F., Graf S., Gupta R.K., Hanrath A.T., Harris J., Hess C., Hewitt S., Hodgson J., Horsfall D., Huang C., Huang N., Hunter K., Janes S.M., Jardine L., Jose S., Kania K., Kennet J., Kilich E., King H.W., Kingston N., Kiselev V.Y., Kourampa J., Kumasaka N., Legchenko E., Lehner P.J., Lindeboom R.G.H., Matara C., Mather M.W., Matheson N.J., McGrath J., Meadows A., Mende N., Mescia F., Morgan M.D., Olabi B., Owehand W.H., O’Brien C., Payne R.P., Polanski K., Price J., Prigmore E., Publico C., Rastall R., Reynolds G., Ribeiro C., Rowlands J., Ruffolo V., Saigal A., Saleh A., Sanchez-Gonzalez A., Saunders C., Schim van der Loeff I.C.D., Scott J., Smith C.M., Smith K.G.C., Spegarova J.S., Stephenson E., Summers C., Sungnak W., Thaventhiran J.E.D., Tordesillas H., Toshner M., Tuong Z.K., van Dongen S., Webb S., Weekes M.P., Wilson C., Wilson N.K., Worlock K.B., Yoshida M.Fuentes:scopus