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scopus(6)
Determination of clozapine and its N-desmethyl metabolite by high-performance liquid chromatography with ultraviolet detection
ArticleAbstract: A rapid high-performance liquid chromatographic method has been developed for the simultaneous deterPalabras claves:Clozapine, N-desmethyl clozapineAutores:Adrián LLerena, Berecz R., De la Rubia A., Norberto M.Fuentes:scopusDetermination of fluoxetine and norfluoxetine in human plasma by high-performance liquid chromatography with ultraviolet detection in psychiatric patients
ArticleAbstract: A rapid high-performance liquid chromatographic method is described for the simultaneous determinatiPalabras claves:Fluoxetine, NorfluoxetineAutores:Adrián LLerena, Berecz R., Cáceres M.C., De la Rubia A., Dorado P., González A.P., Jesus Norberto M.Fuentes:scopusEffect of thioridazine dosage on the debrisoquine hydroxylation phenotype in psychiatric patients with different CYP2D6 genotypes
ArticleAbstract: Sixteen hospitalized white European Spanish psychiatric patients treated with thioridazine alone werPalabras claves:CYP2D6, debrisoquine, Inhibition, ThioridazineAutores:Adrián LLerena, Berecz R., De la Rubia A., Dorado P., Fernández-Salguero P.Fuentes:scopusHigh risk of polydipsia and water intoxication in schizophrenia patients
OtherAbstract:Palabras claves:Autores:Adrián LLerena, De la Rubia A., González I., Penãs-Lledó E.M., Pérez N.Fuentes:scopusRelationship between haloperidol plasma concentration, debrisoquine metabolic ratio, CYP2D6 and CYP2C9 genotypes in psychiatric patients
ArticleAbstract: Background: Around seven percent of Caucasians are poor metabolizers of cytochrome P450, CYP2D6 duePalabras claves:Autores:Adrián LLerena, Berecz R., De la Rubia A., Dorado P.Fuentes:scopusThioridazine steady-state plasma concentrations are influenced by tobacco smoking and CYP2D6, but not by the CYP2C9 genotype
ArticleAbstract: Background: Approximately 7% of Caucasians have genetically impaired activity of the cytochrome P450Palabras claves:Cytochrome p450, pharmacogenetics, smoking, ThioridazineAutores:Adrián LLerena, Berecz R., Dahl M.L., De la Rubia A., Dorado P., Fernández-Salguero P.Fuentes:scopus