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European Journal of Clinical Pharmacology(2)
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scopus(6)
CYP2C9 gene and susceptibility to major depressive disorder
ArticleAbstract: Alteration of monoaminergic neurotransmission has been implicated in the pathophysiology of mood disPalabras claves:CYP2C9 gene, Depression, SchizophreniaAutores:Adrián LLerena, Berecz R., De la Rubia A., Dorado P., González A.P., Penãs-Lledó E.M.Fuentes:scopusIncreased use of second generation antipsychotic drugs in primary care: Potential relevance for hospitalizations in schizophrenia patients
ArticleAbstract: Aim: To analyze the changes in the prescribing pattern of antipsychotic drugs in primary care in ExtPalabras claves:Antipsychotic, drug utilization, Hospitalization, pharmacoepidemiology, Primary Health Care, SchizophreniaAutores:Adrián LLerena, Cáceres M.C., De la Rubia A., Penãs-Lledó E.M.Fuentes:scopusQTc interval lengthening and debrisoquine metabolic ratio in psychiatric patients treated with oral haloperidol monotherapy
OtherAbstract:Palabras claves:debrisoquine, Haloperidol, QTcAutores:Adrián LLerena, Berecz R., De la Rubia A., Dorado P.Fuentes:scopusRelationship between haloperidol plasma concentration, debrisoquine metabolic ratio, CYP2D6 and CYP2C9 genotypes in psychiatric patients
ArticleAbstract: Background: Around seven percent of Caucasians are poor metabolizers of cytochrome P450, CYP2D6 duePalabras claves:Autores:Adrián LLerena, Berecz R., De la Rubia A., Dorado P.Fuentes:scopusRelationship between risperidone and 9-hydroxy-risperidone plasma concentrations and CYP2D6 enzyme activity in psychiatric patients
ArticleAbstract: The implication of cytochrome P450 CYP2D6 enzyme activity in the metabolism of the antipsychotic druPalabras claves:Autores:Adrián LLerena, Berecz R., De la Rubia A., Degrell I., Dorado P., Gómez J., Kellermann M.Fuentes:scopusThe role of cytochrome P450 enzymes in the metabolism of risperidone and its clinical relevance for drug interactions
ReviewAbstract: In the recent years it has been increasingly recognized that pharmacogenetical factors play an imporPalabras claves:CYP2D6, CYP3A4, metabolism, pharmacogenetics, RisperidoneAutores:Adrián LLerena, Berecz R., Cáceres M.C., De la Rubia A., Degrell I., Dorado P.Fuentes:scopus