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Active immunization with human interleukin-15 induces neutralizing antibodies in non-human primates
ArticleAbstract: Background: Interleukin-15 is an immunostimulatory cytokine overexpressed in several autoimmune andPalabras claves:Alum, CTLL-2 cells, Cytokine, IL-15, Immunization, Neutralizing Abs, non-human primatesAutores:Besada-Pérez V., Castro-Velazco J., Chico-Capote A., Eugenio Hardy, Gerónimo-Pérez H., Martínez-Castillo R., Martínez-Cordovez K., Morera-Díaz Y., Puente-Pérez P., Rodríguez-Álvarez Y., Santos-Savio A.Fuentes:scopusDisplaying human interleukin-2 on the surface of bacteriophage
ArticleAbstract: Previous attempts to produce active human Interleukin-2 (hIL-2) in E. coli have failed, due to its aPalabras claves:Interleukin-2, pelB, phage display, Secretion in E. coliAutores:Araña M.J., Callejo M., Chinea G., Gavilondo J.V., Ojalvo A.G., Santiago Nelson Vispo, Santos-Savio A.Fuentes:scopusImmunogenicity profile in African green monkeys of a vaccine candidate based on a mutated form of human Interleukin-15
ArticleAbstract: Background: Interleukin (IL)-15 is a proinflammatory T-cell growth factor overexpressed in several aPalabras claves:African green monkeys, CTLL-2 cells, IL-15, IL-15 D8SQ108S, neutralizing antibodies, vaccine candidateAutores:Alexey Llópiz-Arzuaga, Batista-Roche L.G., Castro-Velazco J., Martínez-Castillo R., Puente-Pérez P., Rodríguez-Álvarez Y., Santos-Savio A.Fuentes:googlescopus