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Obtention and characterization of the recombinant simian Interleukin-15 in Escherichia coli for the preclinical assessment of an IL-15-based therapeutic vaccine
ArticleAbstract: Recombinant simian IL-15 (siIL-15) was obtained for the preclinical assessment of an anti-human IL-1Palabras claves:CTLL-2 and Kit 225 cells, E. coli, in vitro proliferation assays, Protein, recombinant siIL-15, VaccineAutores:Alexey Llópiz-Arzuaga, Besada-Pérez V., García-Lines D., Martínez-Cordovez K., Ramos-Gómez Y., Rodríguez-Álvarez Y., Santos-Savio A.Fuentes:googlescopusIdentification of the first antagonist peptide that inhibits biological effects of interleukin-15
ArticleAbstract: Interleukin-15 (IL-15) is a pro-inflammatory cytokine that is expressed in several autoimmune and inPalabras claves:Alpha receptor, antagonist, Cytokine, IL-15, peptideAutores:Alexey Llópiz-Arzuaga, Altruda F., Ancisar J.A., Arrieta C.A., Cabrales A., Chico A., Estévez M., Garay H.E., Geronimo H., Guillén-Nieto G.E., Machado A.C., Noda J., Ojeda M., Perea-Rodríguez S.E., Reyes O., Rodríguez-Álvarez Y., Sánchez A., Santos-Savio A., Silengo L., Suaréz J., Vázquez M.Fuentes:googlescopusImmunogenicity profile in African green monkeys of a vaccine candidate based on a mutated form of human Interleukin-15
ArticleAbstract: Background: Interleukin (IL)-15 is a proinflammatory T-cell growth factor overexpressed in several aPalabras claves:African green monkeys, CTLL-2 cells, IL-15, IL-15 D8SQ108S, neutralizing antibodies, vaccine candidateAutores:Alexey Llópiz-Arzuaga, Batista-Roche L.G., Castro-Velazco J., Martínez-Castillo R., Puente-Pérez P., Rodríguez-Álvarez Y., Santos-Savio A.Fuentes:googlescopus