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A bioinformatics study of structural perturbation of 3CL-protease and the HR2-domain of SARS-CoV-2 induced by synergistic interaction with ivermectins
ArticleAbstract: The pandemic caused by SARS-CoV-2 forces drug research to combat it. Ivermectin, an FDA approved antPalabras claves:covid-19, Ivermectin, Molecular docking, molecular dynamics, SARS-COV-2Autores:Alvarado Y.J., González-Paz L.A., Joan R. Vera V., Joan Vera-Villalobos, José Luis Paz, Lossada C.A., Luis S. Moncayo, Pérez A.E., Portillo E., Romero F., San-Blas E.Fuentes:googlescopusCharacterization of the tracrARN-<inf>DR</inf> ARN genetic complex associated with the CRISPR-Cas9 system of the phytosymbiont Acholeplasma palmae: biotechnological interest
ArticleAbstract: The CRISPR-Cas9 technology used in plant biotechnology is based on the use of Cas9 endonucleases toPalabras claves:bioinformatics, Molecular docking, mycoplasma, transactivatorAutores:Arcos D., Castro A., Centanaro P., Cristina Maldonado, Diego Vaca, González-Paz L.A., Lossada C.A., Luis S. Moncayo, Pérez A.E.Fuentes:scopusComparative study of the interaction of ivermectin with proteins of interest associated with SARS-CoV-2: A computational and biophysical approach
ArticleAbstract: The SARS-CoV-2 pandemic has accelerated the study of existing drugs. The mixture of homologs calledPalabras claves:Avermectin, covid-19, Ivermectin, Molecular docking, Molecular dynamic, SARS-COV-2Autores:Alvarado Y.J., Fernández-Materán F.V., González-Paz L.A., Hurtado-León M.L., Jeffreys L.N., Joan R. Vera V., Joan Vera-Villalobos, José Luis Paz, Loroño M.A., Lossada C.A.Fuentes:googlescopusCan Non-steroidal Anti-inflammatory Drugs Affect the Interaction Between Receptor Binding Domain of SARS-COV-2 Spike and the Human ACE2 Receptor? A Computational Biophysical Study
ArticleAbstract: SARS-CoV-2 has caused millions of infections and more than 600,000 deaths worldwide. Despite the larPalabras claves:covid-19, Molecular docking, molecular dynamics, NSAIDS, SARS-COV-2Autores:Alvarado Y.J., Fernández-Materán F.V., González-Paz L.A., Joan Vera-Villalobos, José Luis Paz, Lossada C.A.Fuentes:scopus