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Characterization of two experimental rodent models for evaluating novel drugs for rheumatoid arthritis
ArticleAbstract: Rodent models are widely used to evaluate molecular mechanisms of rheumatoid arthritis (RA) and potePalabras claves:Adjuvant arthritis, autoimmunity, Collagen-induced arthritis, RAT, Rheumatoid ArthritisAutores:Barberá A., Domínguez M.D.C., Hernández A., Lorenzo N., Merino N., Padrón G., Suaréz J., Vázquez A., Vivian Morera CórdovaFuentes:scopusGrowth Hormone Releasing Peptide 6 (GHRP6) reduces liver fibrosis in CCl4 chronically intoxicated rats
ArticleAbstract: Tissue fibrosis is a leading cause of morbidity and mortality. Current treatments for conditions sucPalabras claves:Carbon tetrachloride, Cirrhosis, Cytoprotection, FIBROSIS, GHRP6, Liver, SecretagogueAutores:Abreu A., Berlanga-Acosta J., Bringas R., Cibrín D., Cintado A., Coro-Antich R., Cosme-Díz K., Cruz Y., Fernández-Massó J.R., García-del Barco D., González-Ferrer Y., Guillén I., Guillén-Nieto G.E., I. Howland-Álvarez, Inés L., Ivón Howland-Álvarez, León-Fernández O.S., López-Mola E., Mendoza-Marí Y., Miranda J., Nazabal M., Ochagavía M.E., Palenzuela D., Suaréz J., Ugarte-Moreno D., Vázquez-Blomquist D., Vila J.M.Fuentes:googlescopusIdentification of the first antagonist peptide that inhibits biological effects of interleukin-15
ArticleAbstract: Interleukin-15 (IL-15) is a pro-inflammatory cytokine that is expressed in several autoimmune and inPalabras claves:Alpha receptor, antagonist, Cytokine, IL-15, peptideAutores:Alexey Llópiz-Arzuaga, Altruda F., Ancisar J.A., Arrieta C.A., Cabrales A., Chico A., Estévez M., Garay H.E., Geronimo H., Guillén-Nieto G.E., Machado A.C., Noda J., Ojeda M., Perea-Rodríguez S.E., Reyes O., Rodríguez-Álvarez Y., Sánchez A., Santos-Savio A., Silengo L., Suaréz J., Vázquez M.Fuentes:googlescopusPreclinical safety demonstration of the human recombinant erythropoietin HEBERITRO®
ArticleAbstract: Erythropoietin (EPO) is a glycoprotein that appears in blood as a response to hypoxia, acting on bonPalabras claves:EPREX®, erythropoietin, Preclinical toxicology, safetyAutores:Bacardí D.M., Cosme K., Gutiérrez A., I. Howland-Álvarez, Ivón Howland-Álvarez, Merino N., Pérez-Caballero M., Porras D.N., Suaréz J., Urquiza D., Vázquez A.Fuentes:googlescopus