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Applicability of ENCHANTED trial results to current acute ischemic stroke patients eligible for intravenous thrombolysis in England and Wales: Comparison with the Sentinel Stroke National Audit Programme registry
ArticleAbstract: Background: Randomized controlled trials provide high-level evidence, but the necessity to include sPalabras claves:acute ischemic stroke, Alteplase, Clinical trial, health outcomes, thrombolysisAutores:Arima H., Bath P.M.W., Bray B.D., Broderick J.P., Chalmers J., Durham A.C., Kim J.S., Lavados P.M., Lee T.H., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Paley L., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., Rudd A.G., S Anderson C., Sharma V.K., Sprigg N., Wang J.G., Wang X., Woodward M.Fuentes:scopusLow-Versus Standard-Dose Alteplase in Patients on Prior Antiplatelet Therapy the ENCHANTED Trial (Enhanced Control of Hypertension and Thrombolysis Stroke Study)
Conference ObjectAbstract: Background and Purpose'Many patients receiving thrombolysis for acute ischemic stroke are on prior aPalabras claves:aspirin, Brain Infarction, Hypertension, intracranial hemorrhages, Tissue plasminogen activatorAutores:Arima H., Bath P.M.W., Billot L., Broderick J.P., Chalmers J., Demchuk A.M., Donnan G.A., Kim J.S., Lavados P.M., Lee T.H., Lindley R.I., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sato S., Sharma V.K., Wang J.G., Wang X., Woodward M.Fuentes:scopusRationale, design, and progress of the ENhanced Control of Hypertension ANd Thrombolysis strokE stuDy (ENCHANTED) trial: An international multicenter 2×2 quasi-factorial randomized controlled trial of low- vs. standard-dose rt-PA and early intensive vs. guideline-recommended blood pressure lowering in patients with acute ischaemic stroke eligible for thrombolysis treatment
ArticleAbstract: Rationale: Controversy exists over the optimal dose of intravenous (iv) recombinant tissue plasminogPalabras claves:Acute ischaemic stroke, Alteplase, Dose, Hypertension, Rt-PA, thrombolysisAutores:Arima H., Bath P.M.W., Broderick J.P., Chalmers J., Chen X., Demchuk A.M., Donnan G.A., Fuentes S., Huang Y., Kim J.S., Lavados P.M., Lee T.H., Levi C., Lindley R.I., Martins S.O., Nguyen T.H., Octavio Marques Pontes-Neto, Olavarria V.V., Pandian J.D., Parsons M.W., Ricci S., Robinson T.G., S Anderson C., Sharma V.K., Silva-Sieger F.A., Stapf C., Wang J.G., Woodward M.Fuentes:scopus