Mostrando 10 resultados de: 19
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Drug Metabolism and Drug Interactions(3)
Pharmacogenomics(3)
Frontiers in Physiology(2)
Pharmacogenomics Journal(2)
Revista de Biologia Tropical(2)
A rapid and simple LC-MS/MS method for the simultaneous evaluation of CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 hydroxylation capacity
ArticleAbstract: Background: The analytical method here reported for the CEIBA cocktail approach has been developed aPalabras claves:Autores:Adrián LLerena, de Andrés F., Sosa-Macías M.G.Fuentes:scopusCytochrome P450 genetic polymorphisms of Mexican indigenous populations
ReviewAbstract: This review focuses on the genetic polymorphisms of the cytochrome P450 (CYP) genes in Mexican indigPalabras claves:Amerindians, Cytochrome p450, polymorphismsAutores:Adrián LLerena, Sosa-Macías M.G.Fuentes:scopusCYP2D6 gene polymorphisms and pbkp_redicted phenotypes in eight indigenous groups from northwestern Mexico
ArticleAbstract: Aim: Polymorphisms in CYP2D6 impact the interindividual and interethnic variability of drug efficienPalabras claves:allele frequency, CYP2D6polymorphism, Mexican indigenous, pbkp_redicted phenotype, pharmacogeneticsAutores:Adrián LLerena, Galaviz-Hernandez C., Garza-Veloz I., Lazalde-Ramos B.P., Martínez-Fierro M.L., Naranjo M.E.G., Sosa-Macías M.G.Fuentes:scopusCYP450 Genotype/Phenotype Concordance in Mexican Amerindian Indigenous Populations-Where to from Here for Global Precision Medicine?
ArticleAbstract: Global precision medicine demands characterization of drug metabolism and phenotype variation in divPalabras claves:Biomarkers, developing world omics, drug metabolism variation, global personalized medicine, Systems DiagnosticsAutores:Adrián LLerena, de Andrés F., Naranjo M.E.G., Ramos B., Sosa-Macías M.G.Fuentes:scopusEthnic background and CYP2D6 genetic polymorphisms in Costa Ricans
ArticleAbstract: CYP2D6 differences have already been demonstrated within Latin American populations by the CEIBA.FPPalabras claves:Afro-Caribbean, Amerindian, COSTA RICA, CYP2D6, MESTIZO, Poor metabolizers, populations, Ultrarapid metabolizersAutores:Adrián LLerena, Barrantes R., Calzadilla L.R., Céspedes-Garro C., Enrique Terán, Estévez-Carrizo F.E., Grazina M., Jiménez-Arce G., López-López M., María-Eugenia G.N., Moya G.E., Ortiz-López R., Ramírez-Roa R., Rodeiro I., Sarmiento A.P., Sosa-Macías M.G., Tarazona-Santos E.M.Fuentes:scopusPaternal determinants in preeclampsia
ReviewAbstract: Preeclampsia is a condition associated with high rates of maternal-fetal morbidity and mortality. ItPalabras claves:Genetics, Immunology, Paternal, PLACENTA, Preeclampsia, PrimipaternityAutores:Enrique Terán, Galaviz-Hernandez C., Garcia-Ortiz J.E., Lazalde-Ramos B.P., Sosa-Macías M.G.Fuentes:googlescopusInfluence of admixture components on CYP2C9*2 allele frequency in eight indigenous populations from Northwest Mexico
ArticleAbstract: We previously documented the lowest frequency of CYP2C9*2 in Mexican indigenous Tepehuanos followedPalabras claves:ancestral components, CYP2C9, Mexican indigenous, pharmacogeneticsAutores:Adrián LLerena, Dorado P., Galaviz-Hernandez C., Lazalde-Ramos B.P., Licinio J., Martínez-Fierro M.L., Martínez-Sevilla V.M., Rangel-Villalobos H., Salazar-Flores J., Sosa-Macías M.G., Wong M.L.Fuentes:scopusInterethnic variability in CYP2D6, CYP2C9, and CYP2C19 genes and pbkp_redicted drug metabolism phenotypes among 6060 ibero-and native Americans: RIBEF-CEIBA consortium report on population pharmacogenomics
ArticleAbstract: Pharmacogenetic variation in Latin Americans is understudied, which sets a barrier for the goal of gPalabras claves:Amerindians, CYP2C19, CYP2C9, CYP2D6, drug metabolism, LATIN AMERICANS, pharmacogenetics, Precision MedicineAutores:Adrián LLerena, Alvárez M., Barrantes R., Borbón-Orejuela A., Calzadilla L.R., Céspedes-Garro C., Cobaleda J., de Andrés F., Delgado R., Dorado P., Enrique Terán, Estévez-Carrizo F.E., Fcrreiro V., Francisco J.López Hernández, Fricke-Galindo I., Galaviz-Hernandez C., Garza-Ocañas L., Gilman R.H., Gouveia M.H., Grazina M., Humberto Fariñas, Jiménez-Arce G., Jung-Cook H., Lares-Aseff I., Lazalde-Ramos B.P., López-López M., Monroy-Jaramillo N., Moya G.E., Naranjo M.E.G., Ortega-Vázquez A., Ortiz-López R., Penãs-Lledó E.M., Pérez B., Pérez-Páramo Y.X., Ramírez-Roa R., Remírez D., Rodeiro I., Rodrigues-Soares F., Rojas-Martinez A., Santiago Terán, Sarmiento A.P., Scliar M.O., Sosa-Macías M.G., Tarazona-Santos E.M., Tinoco C.A., Zamudio R.Fuentes:googlescopusMitochondria and coenzyme Q10 in the pathogenesis of preeclampsia
ReviewAbstract: Hypertensive disorders during pregnancy constitute one of the main causes of maternal and perinatalPalabras claves:Coenzyme Q10, Mitochondria, PLACENTA, Preeclampsia, PregnancyAutores:Andrés Calle, Enrique Terán, Galaviz-Hernandez C., Gustavo Molina, Isabel Hernández, Leandro R. Tana, Santiago Terán, Sosa-Macías M.G.Fuentes:googlescopusPharmacogenetics and ethnicity: relevance for clinical implementation, clinical trials, pharmacovigilance and drug regulation in Latin America
Conference ObjectAbstract: Congress of Pharmacogenetics and Personalized Medicine. Ethnicity, clinical implementation and regulPalabras claves:clinical trials, Latin American populations, metabolic genotypes, Metabolic phenotypes, native populations, pharmacogenetics, pharmacovigilanceAutores:Adrián LLerena, Altamirano C., Céspedes-Garro C., Enrique Terán, Francisco J.López Hernández, Galaviz-Hernandez C., Humberto Fariñas, Jung-Cook H., López-López M., MARTHA FORS, Martha M. Fors-López, Moya G.E., Ramirez R., Remírez D., Sosa-Macías M.G., Tarazona-Santos E.M., William F. WatersFuentes:googlescopus