Mostrando 10 resultados de: 19
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Drug Metabolism and Drug Interactions(3)
Pharmacogenomics(3)
Frontiers in Physiology(2)
Pharmacogenomics Journal(2)
Revista de Biologia Tropical(2)
Association of ABCB1, ABCC5 and xanthine oxidase genetic polymorphisms with methotrexate adverse reactions in Mexican pediatric patients with ALL
ArticleAbstract: Background: Acute lymphoblastic leukemia (ALL) is one of the most frequent oncological disorders inPalabras claves:Atp-Binding Cassette Transporter Gene, drug therapy/genetics, Genetic Polymorphisms, methotrexate, pharmacovigilance, precursor cell lymphoblastic leukemia-lymphoma/, xanthine oxidase (XO)Autores:Almanza-Reyes H., Chairez-Hernández I., Fausto Zaruma-Torres, Galaviz-Hernandez C., Lares-Asseff I., Loera-Castañeda V., Reyes-Espinoza A., Sosa-Macías M.G.Fuentes:rraaescopusA rapid and simple LC-MS/MS method for the simultaneous evaluation of CYP1A2, CYP2C9, CYP2C19, CYP2D6 and CYP3A4 hydroxylation capacity
ArticleAbstract: Background: The analytical method here reported for the CEIBA cocktail approach has been developed aPalabras claves:Autores:Adrián LLerena, de Andrés F., Sosa-Macías M.G.Fuentes:scopusCytochrome P450 genetic polymorphisms of Mexican indigenous populations
ReviewAbstract: This review focuses on the genetic polymorphisms of the cytochrome P450 (CYP) genes in Mexican indigPalabras claves:Amerindians, Cytochrome p450, polymorphismsAutores:Adrián LLerena, Sosa-Macías M.G.Fuentes:scopusCYP2C9 allele frequency differences between populations of Mexican-Mestizo, Mexican-Tepehuano, and Spaniards
ArticleAbstract: Earlier we had found that the CYP2C9*2 allelic frequency was lower in Mexican-Americans living in CaPalabras claves:CYP2C9, Hispanics, Mexican-Americans, Mexican-Mestizos, Mexican-Tepehuanos, pharmacogeneticsAutores:Adrián LLerena, Alanis-Bãuelos R.E., Dorado P., Lares-Asseff I., Licinio J., Penãs-Lledó E.M., Sosa-Macías M.G., Wong M.L.Fuentes:scopusCYP2D6 gene polymorphisms and pbkp_redicted phenotypes in eight indigenous groups from northwestern Mexico
ArticleAbstract: Aim: Polymorphisms in CYP2D6 impact the interindividual and interethnic variability of drug efficienPalabras claves:allele frequency, CYP2D6polymorphism, Mexican indigenous, pbkp_redicted phenotype, pharmacogeneticsAutores:Adrián LLerena, Galaviz-Hernandez C., Garza-Veloz I., Lazalde-Ramos B.P., Martínez-Fierro M.L., Naranjo M.E.G., Sosa-Macías M.G.Fuentes:scopusCYP450 Genotype/Phenotype Concordance in Mexican Amerindian Indigenous Populations-Where to from Here for Global Precision Medicine?
ArticleAbstract: Global precision medicine demands characterization of drug metabolism and phenotype variation in divPalabras claves:Biomarkers, developing world omics, drug metabolism variation, global personalized medicine, Systems DiagnosticsAutores:Adrián LLerena, de Andrés F., Naranjo M.E.G., Ramos B., Sosa-Macías M.G.Fuentes:scopusGenetic polymorphisms associated to folate transport as pbkp_redictors of increased risk for acute lymphoblastic leukemia in Mexican children
ArticleAbstract: Acute lymphoblastic leukemia (ALL) is a frequent neoplasia occurring in children. The most commonlyPalabras claves:Acute lymphoblastic leukemia, Folate transporters, Genetic Polymorphisms, methotrexate, Molecular epidemiologyAutores:Fausto Zaruma-Torres, Galaviz-Hernandez C., Lares-Asseff I., Lima A., Loera-Castañeda V., María Cristina Arias-Peláez, Quiñones L.A., Reyes-Espinoza A., Reyes-López M., Sosa-Macías M.G.Fuentes:scopusEvaluation of drug-metabolizing enzyme hydroxylation phenotypes in Hispanic populations: The CEIBA cocktail
ReviewAbstract: Interindividual differences in response to drug treatments are mainly caused by differences in drugPalabras claves:Cocktail, Cytochrome P450 (CYP), Genotype, Hispanics, PhenotypeAutores:Adrián LLerena, Alonso-Vilatela E., Alvárez M., Barrantes R., Borbón-Orejuela A., Calzadilla L.R., Céspedes-Garro C., Cobaleda J., de Andrés F., Delgado R., Dorado P., Enrique Terán, Estévez-Carrizo F.E., Ferreiro V., Fiedler J., Francisco J.López Hernández, Galaviz-Hernandez C., Garza-Ocañas L., González-Vacarezza N., Grazina M., Herrera L., Jiménez-Arce G., Lares-Asseff I., Lazalde-Ramos B.P., Leonardo J. Beltrán, López-López M., Monroy-Jaramillo N., Moya G.E., Naranjo M.E.G., Natalia Heras, Ochoa-Morales A., Ortega-Vázquez A., Ortiz-López R., Penãs-Lledó E.M., Pérez B., Pérez-Páramo Y.X., Ramírez-Roa R., Remírez D., Rodeiro I., Rojas-Martinez A., Rojas-Ponce R., Sarmiento A.P., Sosa-Macías M.G., Tarazona-Santos E.M., Vázquez T.C., Yescas-Gómez P.Fuentes:scopusEthnic background and CYP2D6 genetic polymorphisms in Costa Ricans
ArticleAbstract: CYP2D6 differences have already been demonstrated within Latin American populations by the CEIBA.FPPalabras claves:Afro-Caribbean, Amerindian, COSTA RICA, CYP2D6, MESTIZO, Poor metabolizers, populations, Ultrarapid metabolizersAutores:Adrián LLerena, Barrantes R., Calzadilla L.R., Céspedes-Garro C., Enrique Terán, Estévez-Carrizo F.E., Grazina M., Jiménez-Arce G., López-López M., María-Eugenia G.N., Moya G.E., Ortiz-López R., Ramírez-Roa R., Rodeiro I., Sarmiento A.P., Sosa-Macías M.G., Tarazona-Santos E.M.Fuentes:scopusPaternal determinants in preeclampsia
ReviewAbstract: Preeclampsia is a condition associated with high rates of maternal-fetal morbidity and mortality. ItPalabras claves:Genetics, Immunology, Paternal, PLACENTA, Preeclampsia, PrimipaternityAutores:Enrique Terán, Galaviz-Hernandez C., Garcia-Ortiz J.E., Lazalde-Ramos B.P., Sosa-Macías M.G.Fuentes:googlescopus