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Changes in oxidative stress parameters and neurodegeneration markers in the brain of the senescence-accelerated mice SAMP-8
ArticleAbstract: The senescence-accelerated strains of mice (SAMP) are well-characterized animal models of senescencePalabras claves:Calpain, Catalase, Neurodegeneration, Oxidative Stress, Senescence, TauAutores:Antoni Camins, Canudas A.M., Gutiérrez-Cuesta J., Mallol J., Mulero M., Pallás M., Romeu M., Sureda F.X.Fuentes:scopusChronic administration of melatonin reduces cerebral injury biomarkers in SAMP8
ArticleAbstract: Certain effects of melatonin on senescence were investigated. The experimental model used was 10-monPalabras claves:aging, ck5/p35, GSK3β, Oxidative Stress, SAMP8, TauAutores:Antoni Camins, Caballero B., Canudas A.M., Coto-Montes A., Gutiérrez-Cuesta J., Pallás M., Romeu M., Sureda F.X.Fuentes:scopusC-phycocyanin protects cerebellar granule cells from low potassium/serum deprivation-induced apoptosis
ArticleAbstract: We tested the potential cytoprotective role of C-phycocyanin in rat cerebellar granule cell culturesPalabras claves:apoptosis, C-Phycocyanin, cell cycle, Cerebellar granule cells, Flow cytometry, Laser scanning cytometry, Oxidative Stress, RATAutores:Antoni Camins, Camarasa J., Escubedo E., González R., Jiménez A., Pallás M., Pubill D., Rimbau V., Romay C., Sureda F.X.Fuentes:scopusAn overview of investigational antiapoptotic drugs with potential application for the treatment of neurodegenerative disorders
ReviewAbstract: Importance of the field: The increase in life expectancy in developed countries has given rise to sePalabras claves:Alzheimer's disease, apoptosis, Neuroprotective drugs, Parkinson's DiseaseAutores:Antoni Camins, Folch J., Junyent F., Pallás M., Sureda F.X., Verdaguer E., Zárate C.B.Fuentes:scopusAntiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopus3-Amino thioacridone, a selective cyclin-dependent kinase 4 inhibitor, attenuates kainic acid-induced apoptosis in neurons
ArticleAbstract: The mechanisms underlying selective neuronal cell death in kainic acid-mediated neurodegeneration arPalabras claves:cell cycle, Cyclin-dependent kinases, Excitotoxicity, Neurodegenerative illnessAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., Jiménez A., Jordá E.G., Pallás M., Pubill D., Rimbau V., Sureda F.X., Verdaguer E.Fuentes:scopusA flow cytometric study of N-methyl-D-aspartate effects on dissociated cerebellar cells
ArticleAbstract: The effects of N-methyl-D-aspartate (NMDA) on the generation of intracellular reactive oxygen speciePalabras claves:calcium, Cerebellum, Flow cytometry, granule cell, Indo-1, MK-801, NMDA, Oxidative StressAutores:Antoni Camins, Camarasa J., Escubedo E., Sureda F.X., Trullàs R.Fuentes:scopusCyclosporin A enhances colchicine-induced apoptosis in rat cerebellar granule neurons
ArticleAbstract: 1 Cyclosporin A (CsA, 1-50 μM), an immunosuppressive drug with known neurotoxic effects, did not decPalabras claves:CDK5, colchicine, Cyclosporin A, flavopiridol, Neurotoxicity, RoscovitineAutores:Antoni Camins, Canudas A.M., Jiménez A., Jordá E.G., Pallás M., Rimbau V., Sureda F.X., Verdaguer E.Fuentes:scopusDNA low-density array analysis of colchicine neurotoxicity in rat cerebellar granular neurons
ArticleAbstract: Cytoskeletal alteration is a key factor in neurodegenerative processes like Alzheimer's or ParkinsonPalabras claves:Acute toxicity, apoptosis, caspase, cell cycle, Cerebellar granule neurons, colchicine, Oxidative StressAutores:Alvira D., Antoni Camins, Folch J., Forsby A., Pallás M., Rimbau V., Sureda F.X., Yeste-Velasco M.Fuentes:scopusActivation of ataxia telangiectasia muted under experimental models and human Parkinson's disease
ArticleAbstract: In the present study we demonstrated that neurotoxin MPP +-induced DNA damage is followed by ataxiaPalabras claves:apoptosis, ATM, B65 neuroblastoma, cell cycle, MPP +, Parkinson's Disease, Retinoblastoma proteinAutores:Alvira D., Antoni Camins, de la Torre A.V., Ferrer I., Folch J., Gutiérrez-Cuesta J., Jordan J., Junyent F., Pallás M., Pizarro J.G., Sureda F.X., Verdaguer E.Fuentes:scopus