Mostrando 10 resultados de: 11
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NeuroToxicology(2)
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Expert Opinion on Investigational Drugs(1)
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scopus(11)
C-phycocyanin protects cerebellar granule cells from low potassium/serum deprivation-induced apoptosis
ArticleAbstract: We tested the potential cytoprotective role of C-phycocyanin in rat cerebellar granule cell culturesPalabras claves:apoptosis, C-Phycocyanin, cell cycle, Cerebellar granule cells, Flow cytometry, Laser scanning cytometry, Oxidative Stress, RATAutores:Antoni Camins, Camarasa J., Escubedo E., González R., Jiménez A., Pallás M., Pubill D., Rimbau V., Romay C., Sureda F.X.Fuentes:scopusAn overview of investigational antiapoptotic drugs with potential application for the treatment of neurodegenerative disorders
ReviewAbstract: Importance of the field: The increase in life expectancy in developed countries has given rise to sePalabras claves:Alzheimer's disease, apoptosis, Neuroprotective drugs, Parkinson's DiseaseAutores:Antoni Camins, Folch J., Junyent F., Pallás M., Sureda F.X., Verdaguer E., Zárate C.B.Fuentes:scopusAntiapoptotic drugs: A therapautic strategy for the prevention of neurodegenerative diseases
ReviewAbstract: The purpose of this review is to discuss potential pathways involved in the pathogenesis of neurodegPalabras claves:Alzheimer's disease, apoptosis, Cyclin-dependent kinases, Glutamate receptors, Neuronal cell death, Neuroprotective drugs. apoptosis, Parkinson's DiseaseAutores:Antoni Camins, Auladell C., Canudas A.M., Folch J., Junyent F., Pallás M., Pelegrí Gabalda C., Sureda F.X., Verdaguer E., Vilaplana J., Zárate C.B.Fuentes:scopusActivation of ataxia telangiectasia muted under experimental models and human Parkinson's disease
ArticleAbstract: In the present study we demonstrated that neurotoxin MPP +-induced DNA damage is followed by ataxiaPalabras claves:apoptosis, ATM, B65 neuroblastoma, cell cycle, MPP +, Parkinson's Disease, Retinoblastoma proteinAutores:Alvira D., Antoni Camins, de la Torre A.V., Ferrer I., Folch J., Gutiérrez-Cuesta J., Jordan J., Junyent F., Pallás M., Pizarro J.G., Sureda F.X., Verdaguer E.Fuentes:scopusDNA low-density array analysis of colchicine neurotoxicity in rat cerebellar granular neurons
ArticleAbstract: Cytoskeletal alteration is a key factor in neurodegenerative processes like Alzheimer's or ParkinsonPalabras claves:Acute toxicity, apoptosis, caspase, cell cycle, Cerebellar granule neurons, colchicine, Oxidative StressAutores:Alvira D., Antoni Camins, Folch J., Forsby A., Pallás M., Rimbau V., Sureda F.X., Yeste-Velasco M.Fuentes:scopusEvaluation of pathways involved in pentachlorophenol-induced apoptosis in rat neurons
ArticleAbstract: Pentachlorophenol (PCP) (C6HCl5O) is a synthetic toxic organochloride fungicide for humans which exhPalabras claves:Acute toxicity, apoptosis, caspase, cell cycle, Cerebellar granule neurons, Oxidative Stress, PentachlorophenolAutores:Alvira D., Antoni Camins, Bordas M., de la Torre A.V., Folch J., López-Querol M., Pallás M., Rimbau V., Sureda F.X., Yeste-Velasco M.Fuentes:scopusEvaluation of transcriptional activity of caspase-3 gene as a marker of acute neurotoxicity in rat cerebellar granular cells
ArticleAbstract: Caspase-3 is a key protein involved in the classical apoptosis mechanism in neurons, as in many othePalabras claves:Acute toxicity, apoptosis, Caspase-3, Cell-cycle, Cerebellar granule neurons, Oxidative StressAutores:Alvira D., Antoni Camins, Folch J., Forsby A., López-Querol M., Pallás M., Rimbau V., Sureda F.X., Tajes M.Fuentes:scopusKainic acid-induced neuronal cell death in cerebellar granule cells is not prevented by caspase inhibitors
ArticleAbstract: 1. We examined the role of non-NMDA receptors in kainic acid (KA)-induced apoptosis in cultures of rPalabras claves:Ac-DEVD-CHO, apoptosis, Calpain, Caspases, Cerebellar granule cells, colchicine, glutamate, Kainic acid, Par-4, Z-VAD.fmkAutores:Antoni Camins, Camarasa J., Canudas A.M., Escubedo E., García-Jordà E., Jiménez A., Pallás M., Stranges A., Sureda F.X., Verdaguer E.Fuentes:scopusResveratrol inhibits proliferation and promotes apoptosis of neuroblastoma cells: Role of sirtuin 1
ArticleAbstract: Resveratrol prolongs lifespan and prevent cancer formation; however, the mechanisms are not understoPalabras claves:apoptosis, B65, Caspase 3, Neuroblastoma, Resveratrol, Silent information regulator (SIRT1), sirtinol, Sirtuin 1Autores:Ancrenaz V., Antoni Camins, Folch J., Junyent F., Pallás M., Pizarro J.G., Sureda F.X., Verdaguer E.Fuentes:scopusProsurvival role of JAK/STAT and Akt signaling pathways in MPP <sup>+</sup>-induced apoptosis in neurons
ArticleAbstract: In the present study the role of JAK/STAT and Akt in apoptosis was evaluated in cerebellar granule cPalabras claves:Akt, apoptosis, MPP +, STAT3, Cerebellar granule cellsAutores:Alvira D., Antoni Camins, de la Torre A.V., Folch J., Junyent F., Pallás M., Sureda F.X., Verdaguer E., Yeste-Velasco M., Zárate C.B.Fuentes:scopus