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Identification of a functional hypoxia-responsive element that regulates the expression of the egl nine homologue 3 (egln3/phd3) gene
ArticleAbstract: Low oxygen levels induce an adaptive response in cells through the activation of HIFs (hypoxia-inducPalabras claves:EGL nine homologous protein 3 (EGLN3), HIF proline hydroxylase 3 (HPH3), Hypoxia response element (HRE), Hypoxia-inducible factor (HIF), Proline hydroxylase domain 3 (PHD3), Prolyl hydroxylaseAutores:Alcaide M., Cuevas Y., Manuel Ortiz de Landázuri, Naranjo S., Pescador N., Peso L.D., Villar D.Fuentes:scopusIdentification of a region on hypoxia-inducible-factor prolyl 4-hydroxylases that determines their specificity for the oxygen degradation domains
ArticleAbstract: HIFs [hypoxia-inducible (transcription) factors] are essential for the induction of an adaptive genePalabras claves:EGL nine homologue (EGLN), Hypoxia, Hypoxia-inducible factor (HIF), Oxygen-degradation domain (ODD), Proline hydroxylase domain (PHD), Von Hippel-Lindau protein (VHL protein)Autores:Manuel Ortiz de Landázuri, Peso L.D., Vara-Vega A., Villar D.Fuentes:scopus