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Biodegradable nanoparticles for the treatment of epilepsy: From current advances to future challenges
ReviewAbstract: Epilepsy is the second most prevalent neurological disease worldwide. It is mainly characterized byPalabras claves:Epilepsy, lipid nanoparticles, Nanomedicine, nanotechnology, neurodegenerative diseases, Polymeric nanoparticlesAutores:Antoni Camins, Bonilla L., Cano A., Espina M., Esteruelas G., Ettcheto M., García M.L., Sanchez-Lopez E., Souto E.M.B.Fuentes:scopusArticle dexibuprofen biodegradable nanoparticles: One step closer towards a better ocular interaction study
ArticleAbstract: Ocular inflammation is one of the most prevalent diseases in ophthalmology, which can affect variousPalabras claves:Dexibuprofen, Drug delivery system, Nanoparticles, PLGAAutores:Alsafi Z., Antoni Camins, Calpena A.C., Cano A., Espina M., Esteruelas G., Ettcheto M., García M.L., Muñoz M., Ortiz A., Prat J., Pujol M., Sanchez-Lopez E., Souto E.M.B.Fuentes:scopusDual-drug loaded nanoparticles of Epigallocatechin-3-gallate (EGCG)/Ascorbic acid enhance therapeutic efficacy of EGCG in a APPswe/PS1dE9 Alzheimer's disease mice model
ArticleAbstract: Epigallocatechin-3-gallate (EGCG) is a candidate for treatment of Alzheimer's disease (AD) but its iPalabras claves:Alzheimer's disease, APP/PS1 mice, EGCG, Epigallocatechin gallate, PLGA-PEG, Polymeric nanoparticlesAutores:Antoni Camins, Auladell C., Barenys M., Barroso E., Cano A., Chang J.H., Espina M., Ettcheto M., Folch J., García M.L., Kühne B.A., Souto E.M.B., Turowski P.Fuentes:scopusDevelopment and optimization of Riluzole-loaded biodegradable nanoparticles incorporated in a mucoadhesive in situ gel for the posterior eye segment
ArticleAbstract: Riluzole-loaded PLGA nanoparticles (RLZ-NPs) were developed to improve the biopharmaceutical profilePalabras claves:Gellan gum, glaucoma, In situ gelling gel, PLGA nanoparticles, riluzoleAutores:Antoni Camins, Cano A., Espina M., Esteruelas G., Ettcheto M., García-Torra V., Halbaut L., Luisa García M., Sanchez-Lopez E., Souto E.M.B.Fuentes:scopusExtracellular vesicles, the emerging mirrors of brain physiopathology
ArticleAbstract: Extracellular vesicles are secreted by a wide variety of cells, and their primary functions includePalabras claves:Alzheimer’s disease, exosomes, Extracellular vesicles, Glioblastoma, multiple sclerosis, amyotrophic lateral sclerosis, neurodegenerative diseases, Parkinson’s DiseaseAutores:Antoni Camins, Bernuz M., Boada M., Cano A., de Antonio E.E., Ettcheto M., Martí M., Pividori M.I., Puerta R., Ruíz A., Sanchez-Lopez E., Souto E.M.B.Fuentes:scopusIn vitro, ex vivo and in vivo characterization of PLGA nanoparticles loading pranoprofen for ocular administration
ArticleAbstract: Pranoprofen (PF) is a NSAID considered as a safe anti-inflammatory treatment for strabismus and/or cPalabras claves:Anti-inflammatory efficacy, Corneal permeation, Cytotoxicity cell, Nanoparticles, Poly (lactic/glycolic) acid (PLGA), PranoprofenAutores:Abrego G., Alvarado H., Calpena A.C., Cristina Cañadas, García M.L., Silva A.M., Souto E.M.B.Fuentes:scopusEpigallocatechin-3-gallate PEGylated poly(lactic-co-glycolic) acid nanoparticles mitigate striatal pathology and motor deficits in 3-nitropropionic acid intoxicated mice
ArticleAbstract: Aim: To compare free and nanoparticle (NP)-encapsulated epigallocatechin-3-gallate (EGCG) for the trPalabras claves:3-nitropropionic acid, Epigallocatechin-3-gallate, Huntington's disease, neurodegenerative diseases, PLGA-PEG, Polymeric nanoparticlesAutores:Antoni Camins, Auladell C., Barenys M., Cano A., Espina M., Ettcheto M., Folch J., García M.L., Kühne B.A., Sanchez-Lopez E., Souto E.M.B., Turowski P.Fuentes:scopusExosomes-Based Nanomedicine for Neurodegenerative Diseases: Current Insights and Future Challenges
ReviewAbstract: Neurodegenerative diseases constitute a group of pathologies whose etiology remains unknown in manyPalabras claves:exosomes, Extracellular vesicles, Nanomedicine, nanotechnology, neurodegenerative diseasesAutores:Antoni Camins, Boada M., Cano A., Ettcheto M., Muñoz-Morales Á., Ruíz A., Sanchez-Lopez E., Souto E.M.B.Fuentes:scopusState of the art on toxicological mechanisms of metal and metal oxide nanoparticles and strategies to reduce toxicological risks
ReviewAbstract: Metal nanoparticles have been extensively investigated for different types of pharmaceutical applicaPalabras claves:Metal nanoparticles, Nanoparticles functionalization, Nanoparticles toxicity, Reactive oxygen speciesAutores:Antoni Camins, Barroso E., Cano A., Espina M., Ettcheto M., García M.L., García-Torra V., Sanchez-Lopez E., Souto E.M.B., Vázquez-Carrera M.Fuentes:scopusState-of-the-art polymeric nanoparticles as promising therapeutic tools against human bacterial infections
ReviewAbstract: Infectious diseases kill over 17 million people a year, among which bacterial infections stand out.Palabras claves:Bacterial Infections, Infectious diseases, Nanomedicine, nanotechnology, Polymeric nanoparticlesAutores:Antoni Camins, Cajal Y., Cano A., Espina M., Ettcheto M., García M.L., Lopez-Machado A.L., Rabanal F., Sanchez-Lopez E., Souto E.M.B.Fuentes:scopus