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HIF2α Acts as an mTORC1 Activator through the Amino Acid Carrier SLC7A5
ArticleAbstract: The mammalian target of rapamycin (mTOR) pathway, which is essential for cell proliferation, is reprPalabras claves:Autores:Acosta-Iborra B., Albacete-Albacete L., Aragonés J., de Cárcer G., Elorza A., Giménez-Bachs J.M., Malumbres M., Manuel Ortiz de Landázuri, Marsboom G., Martín del Río R., Meléndez-Rodríguez F., Ordóñez A., Rodríguez-Vaello V., Salinas A., Sánchez-Prieto R., Sánchez‐Madrid F., Serrano-Oviedo L., Soro-Arnáiz I., Vara-Vega A.Fuentes:scopusHypoxia promotes glycogen accumulation through hypoxia inducible factor (HIF)-mediated induction of glycogen synthase 1
ArticleAbstract: When oxygen becomes limiting, cells reduce mitochondrial respiration and increase ATP production thrPalabras claves:Autores:Cifuentes D., Cuevas Y., Garcia-Bermejo M.L., Garcia-Rocha M., Guinovart J., Manuel Ortiz de Landázuri, Ordóñez A., Ortiz-Barahona A., Pescador N., Peso L.D., Saez-Morales D., Vazquez S.N., Villar D.Fuentes:scopusInduction of the mitochondrial NDUFA4L2 protein by HIF-1α decreases oxygen consumption by inhibiting complex i activity
ArticleAbstract: The fine regulation of mitochondrial function has proved to be an essential metabolic adaptation toPalabras claves:Autores:Acosta-Iborra B., Aragonés J., Balsa E., Cadenas S., Corral-Escariz M., Elorza A., Enríquez J.A., Fuertes-Yebra E., López-Bernardo E., Manuel Ortiz de Landázuri, Martínez-Ruiz A., Ordóñez A., Perales-Clemente E., Soro I., Tello D.Fuentes:scopus