Mostrando 10 resultados de: 23
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Chemical Conjugation in Drug Delivery Systems
ReviewAbstract: Cancer is one of the diseases with the highest mortality rate. Treatments to mitigate cancer are usuPalabras claves:Biomolecules, Carriers, covalent bioconjugation, Drug delivery systems, linkersAutores:Alberício F., Alexis Eras, Danna Castillo, Hortensia Rodriguez Cabrera, Santiago Nelson Vispo, Suárez Navarro M.Fuentes:scopusBarbiturate- And Thiobarbituarte-Based s-Triazine Hydrazone Derivatives with Promising Antiproliferative Activities
ArticleAbstract: A new class of compounds, which include s-triazine with pyrimidinetrione or thiopyrimidinedione moiePalabras claves:Autores:Al-Rasheed H.H., Alberício F., B. G. De la Torre, Dahlous K.A., El-Faham A., Sharma A., Sholkamy E.N.Fuentes:scopusBbMP-1, a new metalloproteinase isolated from Bothrops brazili snake venom with in vitro antiplasmodial properties
ArticleAbstract: This study describes the biochemical and functional characterization of a new metalloproteinase namePalabras claves:Antiplasmodial activity, B. brazili, Enzymatic characterization, Functional characterization, Metalloproteinase, Snake venomAutores:Aguiar A.C.C., Alberício F., de Azevedo Calderon L., Fernandes C.F.C., Honório K.M., Kayano A.M., Krettli A.U., Maltarollo V.G., Medeiros P.S.M., Oliveira E., Saulo L. Silva, Simões-Silva R., Soares A.M., Stábeli R.G., Zuliani J.P.Fuentes:scopusAnimal toxins and their advantages in biotechnology and pharmacology
ArticleAbstract:Palabras claves:Autores:Alberício F., de Azevedo Calderon L., Rowan E.G., Saulo L. Silva, Soares A.M., Stábeli R.G.Fuentes:scopus1,3,5-Triazino Peptide Derivatives: Synthesis, Characterization, and Preliminary Antileishmanial Activity
ArticleAbstract: A library of short di-, tri-, and tetra-peptides with an s-triazine moiety at the N terminus and eitPalabras claves:1,3,5-triazine derivatives, antileishmanial compounds, morpholines, Peptides, piperidinesAutores:Abd El-Rahman M.M., Alberício F., B. G. De la Torre, Bekhit A.A., El-Faham A., Khalil H.H., Khattab S.N.Fuentes:scopus2022 FDA TIDES (Peptides and Oligonucleotides) Harvest
ArticleAbstract: A total of 37 new drug entities were approved in 2022; although that year registered the lowest numbPalabras claves:drugs, FDA, gadopiclenol, lutetium ( Lu) vipivotide tetraxetan 177, Oligonucleotides, Peptides, terlipressin, tirzepatide, vutrisiranAutores:Al Musaimi O., Al Shaer D.M., Alberício F., B. G. De la TorreFuentes:scopusCorrigendum: Pyrazolyl-s-triazine with indole motif as a novel of epidermal growth factor receptor/cyclin-dependent kinase 2 dual inhibitors(Front. Chem., (2022), 10, (1078163), 10.3389/fchem.2022.1078163)
OtherAbstract: In the original article, there was an error in the Affiliation for Samha Al Ayoubi2. Instead of “SamPalabras claves:anticancer profile, apoptosis, EGFR/CDK-2, ÍNDOLE, pyrazolyl-s-triazineAutores:Al Ayoubi S., Al Zoubi M., Al-Rasheed H.H., Alberício F., Aldalbahi A., Ali M., Alshaer W., B. G. De la Torre, Barakat A., El-Faham A., Nafie M.S., Shawish I.Fuentes:scopusCell Penetrating Peptides as potential drug carriers
ReviewAbstract: The discovery and development of natural, synthetic or peptidomimetic cell-penetrating peptides (CPPPalabras claves:Blood-brain barrie, Cell penetrating peptides, Molecular transportes, PeptidesAutores:Alberício F., Hortensia Rodriguez Cabrera, Pulido X.C., Royo M.Fuentes:scopusAcetic Acid Mediated for One-Pot Synthesis of Novel Pyrazolyl s-Triazine Derivatives for the Targeted Therapy of Triple-Negative Breast Tumor Cells (MDA-MB-231) via EGFR/PI3K/AKT/mTOR Signaling Cascades
ArticleAbstract: Here, we described the synthesis of novel pyrazole-s-triazine derivatives via an easy one-pot procedPalabras claves:anticancer profile, apoptosis, DMF-DMA, EGFR/PI3K/AKT/mTOR, One-pot synthesis, pyrazolyl-s-triazineAutores:Al Zoubi M., Alberício F., Aldalbahi A., Alqudah D.A., Alshaer W., B. G. De la Torre, Barakat A., Daoud F., El-Faham A., Hatmal M.M., Haukka M., Nafie M.S., Sharma A., Shawish I.Fuentes:scopusAn Androsterone-H<inf>2</inf>@C<inf>60</inf> hybrid: Synthesis, Properties and Molecular Docking Simulations with SARS-Cov-2
ArticleAbstract: We report the synthesis and characterization of a fullerene-steroid hybrid that contains H2@C60 andPalabras claves:cyclopropanation, Fullerenes, Molecular docking, SARS-COV-2, Steroid hybridsAutores:Alberício F., Almagro L., Herranz M.Á., Hortensia Rodriguez Cabrera, Lemos R., Makowski K., Maroto E., Martín N., Molero D., Murata Y., Ortiz O., Suárez Navarro M.Fuentes:scopus